How does ammonium fluoride affect HPLC and LCMS data if using Aqueous Normal Phase ANP methods – FAQ Read More →
Do Cogent TYPE-C Silica columns have a partial positive charge and if so is retention for basic compounds reduced because of this – Tech Information Read More →
Which acid or base additive should I choose for positive or negative ion mode in LC-MS – FAQ Read More →
Should I use methanol as the organic solvent in HPLC when using Aqueous Normal Phase ANP – FAQ Read More →
Blocked HPLC column from proteins from the sample matrix can be recovered – Tips & Suggestions Read More →
Using ammonium acetate or formate in an acetonitrile based HPLC mobile phase for Aqueous Normal Phase ANP – Tips & Suggestions Read More →
LFER studies compared to Log D data in describing the Aqueous Normal Phase ANP retention – Tips & Suggestions Read More →
Using the wavelength calibration solution holmium oxide for HPLC UV detector performance qualification – Tips & Suggestions Read More →
What is the maximum salt concentration to use with Cogent TYPE-C HPLC columns with HPLC or LCMS – FAQ Read More →
What will the pressure be with a mobile phase of 90% methanol and 10% DI water with a 4.6 x 250mm Cogent TYPE-C HPLC column – FAQ Read More →
Aqueous Normal Phase ANP ballistic gradients compared to same in HILIC – Tips & Suggestions Read More →
For sugars analyzed by LCMS sodium acetate is recommended for sensitivity of Na adducts – Tips & Suggestions Read More →
How can Cogent TYPE-C HPLC columns offer faster results compared to other type of silica based columns – FAQ Read More →
I see a strange saw tooth type of pattern in the UV baseline using my Cogent HPLC column what is it and how can I fix it – FAQ Read More →
Using ammonium acetate or triethylamine TEA with Cogent HPLC columns – Tips & Suggestions Read More →
Use a low concentration of salt in your mobile phase to avoid ion suppression and build up on your inlet source – Tips & Suggestions Read More →
Working with ammonium acetate and LCMS requires attention to cleaning – Tips & Suggestions Read More →
What is the difference between related compounds and related substances in pharmaceutical HPLC – FAQ Read More →