How to Repair a Blocked Frit in an HPLC Column – Tips & Suggestions

A simple technique. The frit assembly in all HPLC Columns is a possible site of blockage and resulting high pressures and other possible issues. Rationale: For non UHPLC, the frit pore size is a distribution of sizes with an average of only 2um wide and therefore can be easily blocked by small un-dissolved sample, matrix […]

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