Use a low concentration of salt in your mobile phase to avoid ion suppression and build up on your inlet source – Tips & Suggestions

Many people ask me about the problem associated with polar acidic compound analysis using HILIC or ion exchange columns with Mass Spectrometry. Fortunately, there is an easy solution to this problem. You can use Cogent TYPE-C HPLC columns such as the Diamond Hydride™, Phenyl Hydride™ and others to separate highly polar compounds in Aqueous Normal […]

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What is the structure of the Cogent Phenyl Hydride bonded ligand – FAQ

The Cogent Phenyl Hydride phase is a 4 carbon chain with a phenyl group at the end attached directly to the silica hydride surface with a single, direct silicon-carbon bond. With bonds in traditional silica B based materials, the organo-silane starting material is Si-O-Si-C4-Phenyl and this reagent is reacted with the silica to form the […]

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