Amlodipine, Valsartan, and Hydrochlorothiazide Tablet USP Assay – AppNote

This AppNote demonstrates the USP Method for Amlodipine, Valsartan, and Hydrochlorothiazide Tablets working with the Cogent RP C18. As shown in the Chromatograms, the Peak efficiency is superb and USP Peak tailing guidelines are easily met with the Column. This demonstrates a great alternative Column for easy plug and play with this USP Method. Method […]

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Amoxicillin USP Assay with HPLC – AppNote

Alternate L1 Column used for the USP Assay Method for Amoxicillin This USP Amoxicillin Assay is performed and a five injection overlay shows Run to Run consistency and Precision. The Peak Efficiency is very good and Peak Tailing guidelines are easily met with RSD values less than 0.3%. This demonstrates a good alternate Column for […]

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Cytarabine Assay with HPLC- AppNote

A Reliable Assay for Detection of a Chemotherapeutic   Cytarabine belongs to the category of chemotherapy called antimetabolites. Antimetabolites are very similar to normal substances within the cell. When these substances are incorporated into the cellular metabolism, they are unable to divide. Antimetabolites are cell-cycle specific and target cells at very specific phases in the […]

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Deoxycholic Acid Assay Analyzed with HPLC – AppNote

A Reliable Method for a Bile Acid This Deoxycholic Acid Assay produces Run to Run consistency and Precision with Retention Time RSD values of 0.1%. A sensitive HPLC-UV Method that may be used for quantification in raw material and liquid pharmaceutical formulation is presented. Figure 1. Full Chromatogram Figure 2. Magnified Chromatogram to show peak […]

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Desloratadine Assay with HPLC – AppNote

Alternate L1 Column used for HPLC Method of Desloratadine This Desloratadine Assay is easily performed and the five injection overlay below demonstrates Run to Run consistency and Precision. The Peak Efficiency is very good and Peak Tailing guidelines are easily met with RSD values below 0.3%. This demonstrates a good alternate Column for your Desloratadine […]

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Felodipine Extended-Release Tablets USP Assay – AppNote

USP Method for Felodipine ER Tablets This method presents the USP Felodipine Extended-Release Tablet assay using the Cogent RP C18. As shown in the chromatogram with a five injection overlay, the peak efficiency is superb and USP peak tailing guidelines are easily met with the Cogent RP C18™ column.  This demonstrates a great alternative Column […]

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Fluorouracil Assay Analyzed with HPLC – AppNote

A Reliable Method for a Chemotherapeutic Drug This Fluorouracil Assay is easily performed and demonstrates Run to Run consistency and Precision with Retention Time RSD values below 0.1%. This Method shows reliability for analysis of this Pyrimidine Analog that is an anti-neoplastic anti-metabolite. Peak: Fluorouracil Method Conditions: Column: Cogent RP C18™, 5um, 100Å Catalog No.: […]

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Hydrocortisone USP Assay with HPLC – AppNote

Alternate L1 Column used for the USP Assay Method of Hydrocortisone This USP Hydrocortisone Assay is easily performed and the five injection overlay below demonstrates Run to Run consistency and Precision. The Peak Efficiency is very good and Peak Tailing guidelines are easily met with RSD values of 0.5%. This demonstrates a good alternate Column […]

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Ifosfamide Assay Analyzed with HPLC – AppNote

A Reliable Method for an Antineoplastic Chemotherapeutic Drug This Ifosfamide Assay is easily performed and demonstrates Run to Run consistency and Precision with Retention Time RSD values below 0.8%. This Method shows reliability for analysis of this Pyrimidine analog that is an antineoplastic anti-metabolite. Peak: Ifosfamide Method Conditions: Column: Cogent RP C18™, 5um, 100Å Catalog […]

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Molnupiravir and Favipiravir Analyzed with HPLC – AppNote

Oral Anti-Viral Medications – Easy Reversed Phase Method  Molnupiravir and Favipiravir, new anti-viral drugs were analyzed with HPLC using a simple Mobile Phase. As shown in the 10 injection overlay in the chromatogram below, the Separation, Peak Shapes and Repeatability are very good (%RSD ≤ 0.2).   Peaks: 1. Favipiravir 2. Molnupiravir  Method Conditions: Column: Cogent […]

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Nitrosamine Impurity Assay with HPLC – Extended AppNote

API or Impurity Assay Methods for Sartan Drugs Nitrosamines are highly toxic and are suspected to be a human carcinogen. At high doses, some haven been shown to be a hepatotoxin that causes liver fibrosis and cancer in several animal species. Due to the toxic nature of Nitrosamines, these compounds must be monitored using reliable […]

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Tetracycline USP Assay with HPLC- AppNote

USP Method for Tetracycline This USP Tetracycline Assay is performed and a five injection overlay shows run to run consistency and Precision. The Peak Efficiency is very good and Peak Tailing guidelines are easily met with RSD values less than 0.4%. This demonstrates a good Alternate Column for your USP Method.   Peak: Tetracycline Method Conditions: […]

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