Analyze phosphorylated compounds with the Cogent Diamond Hydride column – Tips & Suggestions Read More →
Are there HPLC columns that could be used to separate both polar and nonpolar compounds in a single run – FAQ Read More →
Assuring retention of polar compounds in an Aqueous Normal Phase ANP gradient in positive ion mode LCMS – Tips & Suggestions Read More →
Biological extracts Diamond Hydride columns and LCMS ion source diminished peak height problem – FAQ Read More →
Blocked HPLC column from proteins from the sample matrix can be recovered – Tips & Suggestions Read More →
Can I use phosphoric acid or sodium phosphate with the Cogent Diamond Hydride HPLC column – FAQ Read More →
Can I use the Cogent Diamond Hydride column without mobile phase additives like formic acid – FAQ Read More →
Causes of high baseline noise with Cogent Diamond Hydride HPLC column – Tips & Suggestions Read More →
Changing retention times of amino acids in biological extracts using ammonium acetate in HPLC methods. – Troubleshooting. Read More →
Glucose pyruvate taurocholic acid gamma glutamylcysteine and other analysis – Tips & Suggestions Read More →
High molecular weight compounds that won’t retain on Cogent Diamond Hydride column try Cogent Bidentate C8 300 – Tips & Suggestions Read More →
High pressure develops after flushing a Cogent Diamond Hydride column with acetonitrile cause and solution – FAQ Read More →
How can I restore my Diamond Hydride HPLC column after I ran out of mobile phase and air was accidently introduced into it – FAQ Read More →
How do I avoid distorted peak shapes when using a basic mobile phase pH for the analysis of a lipophilic amine – FAQ Read More →
How does ammonium fluoride affect HPLC and LCMS data if using Aqueous Normal Phase ANP methods – FAQ Read More →
How often do I need to do the conditioning procedure for a new Diamond Hydride column – FAQ Read More →
How to eliminate retention time drift in LCMS with Aqueous Normal Phase ANP methods – Tips & Suggestions Read More →
How to get improved retention and peak shape for glutamine glutamic acid and aspartic acid – Tips & Suggestions Read More →
How to improve peak shapes, retention & carryover for polar compounds with the Cogent Diamond Hydride™ column – Tips & Suggestions Read More →
How to keep the Cogent Diamond Hydride column clean when using blood as a sample – Tips & Suggestions Read More →
I am not observing any peaks for succinic acid or alpha-ketoglutarate with the Cogent Diamond Hydride column – Tips & Suggestions Read More →
I heard that there is not a good alternative to HILIC to achieve sufficient retention for some compounds – FAQ Read More →
Injection Technique for Aqueous Samples using Cogent TYPE-C Columns in ANP – Tips & Suggestions Read More →
Issues arising from changes in mobile phase with acids to one with ammonium salts. Tips & Suggestions Read More →
Lower retention is observed when functional group in a compound is ionized – Tips & Suggestions Read More →
Mobile Phase recommendation Cogent Diamond Hydride columns for use with serum samples in Aqueous Normal Phase LCMS – Tips & Suggestions Read More →
Modify selectivity in an ANP method of HPLC using different mobile phase pH – Tips & Suggestions Read More →
My LCMS source was getting white film on it and at the same time the background noise was very low so is my Diamond Hydride column bleeding packing material – FAQ Read More →
Polar and non polar peptides analyzed by LCMS with an Aqueous Normal Phase ANP method – Tips & Suggestions Read More →
Restoring the initial results with a method for analyzing AMP ADP ATP UDP and GPT in biological extracts – Tips & Suggestions Read More →
Solving baseline problems in ANP methods with the Cogent Diamond Hydride column – Tips & Suggestions Read More →
