Adsorption can Happen Quickly in an Autosampler Vial.

We have shown from previous experiments of how concentration of certain analytes can be adsorbed to glass surfaces over time which is an indicator of potential problems for the laboratory for many other analytes as well. In this experiment, a sample was taken in small timed increments to display the magnitude of potential sample loss […]

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Are RSA Autosampler Vials Pyrogen Free?

The RSA™ or Reduced Surface Activity autosampler vials are Pyrogen Free when manufactured as they are produced sterile and are never touched by “human hands”. They are then packaged, including shrink wrapped in a sterile, class 100,000 clean room environment. We do not classify these vials as Sterile for sale since the packaging is not sterilized […]

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Are RSA Vials Approved by the FDA for Use in Clinical Testing?

The FDA does not “Approve or Disapprove” of Vials for use in Analytical Testing. Therefore any Vial may be used for this purpose to be Compliant with FDA regulations including the RSA™ Vials. However, if Vials are used for Human Clinical Testing or Packaging of Pharmaceuticals, you might need to Validate and get FDA-certified. Please […]

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Are RSA Vials Suitable for Elemental Analysis?

It depends on the analytical technique you are using. Some sample preparations may contain hydrofluoric acid, in which case you can’t use any type of glass. Polypropylene and Teflon containers are common for ICP-MS because of the lower elemental extractables. In addition to Na, B and Si glass leaches out other elements in trace amounts that […]

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Are the RSA Vial Write-On Patches Ceramic or Painted?

RSA™ vials, both Amber and Clear are supplied with the Write-On Patches are Ceramic and NOT an Epoxy Paint. Lower quality brands vials are supplied with Painted Patches using Epoxy paint, to keep the cost lower but the problem with it is they out-gas while in the packages which causes contamination for some. If you […]

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Are the RSA™ Vials ISO Certified?

No, the RSA™ Vials and Inserts do not come with an ISO Certification. However, the process with which the vials are manufactured is ISO certified.  A certificate of QC Conformance for RSA Vials or Inserts is available upon request. Please contact Customer Service for Assistance to obtain the Certificate. More information about RSA Vials

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Can AQR™ Autosampler Vial Caps be Autoclaved?

Yes, studies were conducted on our AQR Autosampler Vial Screw Caps (similar to 9512C-1MP-RS AQR™) in which they were autoclaved for about half an hour; a gravity cycle of 250 °F  with sterilization time 15 min and dry time 10 min. The Caps exhibited no Physical Defects such as warping or other deforming and continued […]

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Can I buy Tubes made with RSA Glass?

RSA™ Glass is not available in any Tube Format and at this time, RSA or Reduced Surface Activity Glass is only available in 12x32mm Autosampler Vials. These vials will not release any contaminants into chloroform or any other solvent.

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How are RSA™ vials different from all other autosampler vials?

Using patent pending and proprietary processes of precision manufacturing, RSA™ autosampler vials are superior to all other vials on the market since they are not only made to exact tolerances for your autosampler, they are manufactured for your sample chemistry as well. When ordinary and “LCMS Certified” commercially available autosampler vials are made, they are […]

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Is the RSA-Pro Glass Surface Treatment Different than Deactivation of a Regular Vial?

Yes, it is different from ordinary Deactivation/Silanization. When manufacturers “silanize” ordinary glass Vials they apply Silanes that are Hydrophobic. The RSA-Pro™ Treatment bonds a proprietary Hydrocarbon which has Methyl Groups on RSA Glass Surface to make it Hydrophobic. Regular Glass Vials can be covered with Hydroxyl Groups/Silanols and harder to completely cover (silanize) as they […]

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Is there a Difference in Performance between Clear and Amber RSA™ Vials?

Except for the obvious, there is no difference between Amber and Clear RSA glass, chromatographically speaking. Regarding adsorption of Basic Analytes or effect of pH on Sample Diluent, we have not observed any differences from our QC testing and our R&D experiences. Typically one would choose amber over clear glass in situations where light-sensitive analytes […]

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Which Vial Should I use for a Low-Volume Sample Study using Proteins?

Some Compounds adsorb to Borosilicate Glass due to Hydroxyl Groups / Silanols on the Glass Surface and others adsorb due to Hydrophobic Interaction with the Glass itself. Deactivated (surface Treated) RSA-Pro Vials offer the best Glass Options for you since the surface treatment is more complete than any other Glass Vial Available.     RSA Vial […]

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Why Do you Not use a Cleaning Process with RSA Vials?

When Autosampler Vials are manufactured from high purity glass tubing, to eliminate the vertical and horizontal strain on the vials, they must be annealed using heat that is between 1,200 – 1,400°F. At this temperature all organic material is burned off and eliminated leaving vials as clean as can possibly be. However, if the proper […]

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Why does MicroSolv have 4 Tiers or Brands of Autosampler Vials?

A simple and quick answer is to Meet the Different Needs of All Laboratories and Chromatographers. In 1997, the MicroSolv Brand™ Vials, made with N51A TYPE-1 Borosilicate Glass were the standard of the Autosampler Vial Market and were used by many leading Autosampler Manufacturers as their Brand. Made to be Pharmaceutical Grade Vials equal to […]

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