Cogent™ HPLC columns are compatible with ultra high performance liquid chromatography (UHPLC) instrumentation.

However, it is important to note the low pressure produced in Aqueous Normal Phase  ANP and the pressure limits of these columns. The Cogent 2.o™ is considered “Near UHPLC” with pressure limits near 9,000 psi. If you are using ANP HPLC methods it is unlikely you will develop high pressure even at fast run rates due to the very low viscosity of the mobile phase used in these types of methods.