It has been well documented in the literature over the years that using Cogent TYPE-C™ HPLC columns offers chromatographers fast results during method development and even with routine use. How?
1. Faster Equilibration. Due to the unique nature of the column surface, these columns will fully equilibrate, after gradient runs with only 3-5 columns compared to market leading columns which requires 25-40 columns volumes to achieve precision.
2. Run with much faster flow rates. Aqueous Normal Phase ANP methods for polar compound analysis uses a very high concentration of Acetonitrile and therefore lowers the viscosity of the mobile phase by 50-60% over pure water. With this you can increase your flow rate by 2-3 times without suffering band broadening or high back pressure.
3. Smaller Particle sizes. Cogent TYPE-C™ HPLC columns are offered in 4um or 2.2um allowing for “near UHPLC efficiency” without the sever back pressure which is typical.
Faster means more runs and more data.