I heard that there is not a good alternative to HILIC to achieve sufficient retention for some compounds – FAQ Read More →
I see a strange saw tooth type of pattern in the UV baseline using my Cogent HPLC column what is it and how can I fix it – FAQ Read More →
Increasing selectivity and resolution for a xylose and ribose method – Tips & Suggestions Read More →
Is TFA or formic acid better as an acidic mobile phase additive for Cogent TYPE-C columns – FAQ Read More →
Is TYPE-C Silica a high purity support and have a low metal content silica like Type B silica – FAQ Read More →
My LCMS source was getting white film on it and at the same time the background noise was very low so is my Diamond Hydride column bleeding packing material – FAQ Read More →
My method uses an standard type-B silica based HPLC column is there a Cogent TYPE-C column equivalent substitute – FAQ Read More →
No need to use a high pH mobile phases for compounds with a high pKa – Tips & Suggestions Read More →
Should I use methanol as the organic solvent in HPLC when using Aqueous Normal Phase ANP – FAQ Read More →
Since Cogent TYPE-C columns can be used in Reversed Phase or Normal Phase what do you suggest to switch these solvent systems which are not miscible – FAQ Read More →
Since Cogent TYPE-C Silica columns use a transition metal catalyst in production what is the presence of any trace quantity on the surface of the stationary phase- FAQ Read More →
The effect of ionic strength of the mobile phase additive for HPLC columns in Aqueous Normal Phase – Tips & Suggestions Read More →
Type of gradient to use for analysis of hydrophilic and hydrophobic molecules in the same HPLC or LCMS run – Tips & Suggestions Read More →
Use a low concentration of salt in your mobile phase to avoid ion suppression and build up on your inlet source – Tips & Suggestions Read More →
What are some notable examples of journal articles that feature Aqueous Normal Phase ANP methods in metabolomics studies – FAQ Read More →
What are some of the advantages of using Cogent TYPE-C prep and semi-prep HPLC columns – FAQ Read More →
What can cause changing retention times and a peak showing up in my blank with a Silica-C column – FAQ Read More →
What effect does high injection volume have on column performance in Aqueous Normal Phase ANP HPLC- FAQ Read More →
