Are polypropylene screw top vials and caps free of metals (sodium, potassium, magnesium, and calcium)?

Polypropylene screw top vials (Item# 9502S-PP-CLEAR) are not tested for metal content. However, we would expect it to be low since metals are not used in the manufacturing process. Since the vial are not tested and after opening the package in environments with metals we can’t guarantee the vials to be metal free. Screw top caps (Item# 9502S-30C-B) are manufactured free […]

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Are RSA Autosampler Vials Pyrogen Free?

The RSA™ or Reduced Surface Activity autosampler vials are Pyrogen Free when manufactured as they are produced sterile and are never touched by “human hands”. They are then packaged, including shrink wrapped in a sterile, class 100,000 clean room environment. We do not classify these vials as Sterile for sale since the packaging is not sterilized […]

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Are the AQ™ Advanced Quality brand of LCMS vials compatible with DMSO?

DMSO is not considered reactive towards any polypropylene vial product. Still, one should always be aware of the possibility when using DMSO with laboratory plastic that under some conditions, extractables from the plastic could result and show up as ghost peaks in the HPLC runs. There are many factors that can affect the likelihood of extractables forming, which […]

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Are the MS-compatible polypropylene vials (Cat No. 9532S-MS) hydrophobic or hydrophilic?

The vial is made of MS-compatible polypropylene, which consists only of repeating hydrocarbon monomer units: These polymers have no polar or ionizable groups so the polypropylene vials are hydrophobic. A primary reason one might use these vials is to avoid undesirable properties of hydrophilic silanols on conventional borosilicate glass vials is their hydrophobicity. The silanolic groups […]

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Are the RSA Vial Write-On Patches Ceramic or Painted?

RSA™ vials, both Amber and Clear are supplied with the Write-On Patches are Ceramic and NOT an Epoxy Paint. Lower quality brands vials are supplied with Painted Patches using Epoxy paint, to keep the cost lower but the problem with it is they out-gas while in the packages which causes contamination for some. If you […]

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Are the RSA™ Vials ISO Certified?

No, the RSA™ Vials and Inserts do not come with an ISO Certification. However, the process with which the vials are manufactured is ISO certified.  A certificate of QC Conformance for RSA Vials or Inserts is available upon request. Please contact Customer Service for Assistance to obtain the Certificate. More information about RSA Vials

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Are your HPLC and GC autosampler vials & caps sealed from outside moisture?

The vials & caps are designed for general HPLC or GC applications. Criteria of quality for BASIK™ and MicroSolv™ Brands include suitable fit for the autosampler (not jamming during injections, etc.) and being contaminant-free from the manufacturing process. Quality criteria for AQ™ Brand includes advanced testing with HPLC and LCMS and criteria for AQ™ Brand with […]

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Autoclaving Inserts with Plastic Springs is Not Recommended.

Autoclaving glass or plastic Inserts with Attached Plastic Springs is not recommended. While the glass can withstand temperatures up to 1,000°F, the Polyethylene Spring will become deformed, may crack and will lose its functionality. You can Sterilize these Inserts through Ethylene Oxide Gas Sterilization. Inserts Product Page  

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Autosampler Vials sold by MicroSolv will Fit Your Instruments.

All Autosampler Vials sold by MicroSolv will fit commercially available modern HPLC Autosamplers. During the vial manufacturing processes, opto-electronic devices in the Vial converting machines check within fractions of a second to ensure the processed Vials meet the physical specifications (fit and form, dimension, etc.). In the case of a mismatch, the vial is blown […]

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Effects of washing and re-using autosampler vials on HPLC data

As reported by Thermo, some laboratories may try to save money by washing their used autosampler vials and reusing them. However, these products are designed to be disposable and reuse can cause numerous QC issues, such as contaminant peaks, sample loss, and physical deformations on the glass surface. Here a clear, clean vial shows virtually no peaks in […]

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Effects of washing and re-using autosampler vials on sample loss

As reported by Thermo, laboratories may try to save money by washing their used autosampler vials and reusing them. However, these products are designed to be disposable and reuse can cause numerous QC issues, such as contaminant peaks, sample loss, and physical deformations on the glass surface. Here a variety of vials are tested for sample loss. It […]

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Effects of washing and re-using autosampler vials on the glass surface

As reported by Thermo Scientific, some budget minded laboratories may try to save money by washing their used autosampler vials and reusing them. However, these products are designed to be disposable and reuse can cause numerous QC issues, such as contaminant peaks, sample loss, and physical deformations on the glass surface. In these microscopy images, you can […]

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How can I minimize bubble formation with limited volume vials?

Vials with small volume internal ID are designed to allow the user to use most of the sample which may be too low for the injection needle to reach with standard, flat-bottom vials. One drawback, is that filling microvials can lead to bubble formation in some cases requiring the user to physically shake the bubble […]

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Is Formic Acid Compatible with Borosilicate Glass? – FAQ

Yes, Formic Acid is Generally Compatible with Borosilicate Glass. There are two aspects that one needs to be mindful of when storing Formic Acid in Glass Vials or Glass Inserts: Formic Acid gradually decomposes to Carbon Monoxide (CO) and Water, building up pressure inside the container. The warmer the solution the faster the process. Therefore, […]

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Is the PTFE in the screw cap 9509S-10C-B “cast” or “skived”?

The PTFE is “cast” for the AQR™ septa in the screw caps which includes our catalog number 9509S-10C-B as well as many other AQR brand screw and snap caps. It is much easier to control the quality of “cast” PTFE over the “skived” PTFE which results in much better reliability and performance from batch to batch. The […]

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PFAS Analysis using Glass or Plastic Vials – Tips and Suggestions

In order to take the most accurate accurate analysis of PFAS Special Care must be taken for storage and sampling. Glass and also low-density polyethylene (LDPE) materials are not recommended for storing PFAS samples. PFAS can adsorb to glass, particularly when the chemicals are stored in a glass container for extended periods of time. Recommended […]

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Screw and Snap Cap Evaporation Studies

Evaporation of solvent from the autosampler vial can be a significant issue for samples that are left out for several days before analysis. The evaporation can change the concentration of analytes in solution and cause quantitative errors. For these reasons, it is important to know what factors affect evaporation. It is indicated in ivermectin drosten […]

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Silicone rubber in septa for autosampler vials vary in the way it is made.

Silicone rubber is the backbone of most modern septa for chromatography vial caps. But the way the silicone is made will vary from manufacturer to manufacturer and even within the same manufacturer or brand. During the manufacturing process, silicone rubber must be “cured” when it is cross-linked to produce the desired physical properties needed for […]

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Troubleshooting: Fused Insert Vials Break During Injection.

When injecting Samples using Fused Insert Glass Vials, sometimes the Needle hits the Insert Wall, causing it to break. Is this due to the Inserts not being Properly Aligned, vertically? This problem is more likely due to the Needle not being Properly Aligned vertically; this can occur for a number of reasons, which may include: […]

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Understanding Deactivating or Silanizing Glass Vial & Insert Surfaces for Chromatography.

To deactivate glass vials and inserts to minimize adsorption of proteins, peptides and other compounds for laboratory use, a “coating” process using a silicone oil dispersed in a solvent is commonly used. This “mechanically” coated surface of the glass is commonly called “silanizing the glass”. All of MicroSolv’s Deactivated Glass is coated via a superior  improved process called “Reactive Organosilane Bonding” which uses a reactive silane monomer or […]

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What are Soft-Guard™ Septa?

Soft-Guard™ septa are used in HPLC, GC, LCMS or GCMS for autosampler vials when a quality value is desired. Soft-Guard™ septa are made with a unique formulation of high purity silicone rubber and cast PTFE to minimize extractables often found in septa that can cause interfering peaks which lowers the quality of your data. Along […]

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What does Residual Volume mean with Autosampler Vials?

The syringe needle of an autosampler does not go all the way to the bottom of a vial during injection, and therefore some sample will always remain in the vial. This is referred to as the Residual Volume of the Autosampler Vial. Some Vials have a tapered bottom for example, which decreases the Residual Volume. […]

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What is a 9-425 Vial?

Screw top vials and caps that are designed to fit modern autosamplers used in HPLC and GC. Most autosamplers today require a tight tolerance on the fit and form of the autosampler vials and caps. Our engineers have developed a vial and cap system that not only fits most autosamplers, they have instituted an automated […]

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What is the Difference between 45 Shore A and 55 Shore A Septa?

“Shore” is a measure of the hardness of a material, named after Albert F. Shore. The letter designates the “scale,” which specifies what type of substance is described. It is indicated in ivermectin drosten Setakamachi-takayanagi adults and children over 12 years of age for the treatment of nausea and vomiting associated with a variety of […]

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What is the purpose of a partial slit septa?

The partial slit septa offers both a penetration aid for thick and dull needles plus prevents evaporation resulting in concentration changes. Only the silicone rubber is cut, the PTFE is not pre cut acting as an evaporation barrier.

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