Should I use methanol as the organic solvent in HPLC when using Aqueous Normal Phase ANP – FAQ Read More →
Since Cogent TYPE-C columns can be used in Reversed Phase or Normal Phase what do you suggest to switch these solvent systems which are not miscible – FAQ Read More →
The effect of ionic strength of the mobile phase additive for HPLC columns in Aqueous Normal Phase – Tips & Suggestions Read More →
Two gradients to use for analysis of hydrophilic and or hydrophobic molecules in the same Aqueous Normal Phase ANP method – Tips & Suggestions Read More →
Type of gradient to use for analysis of hydrophilic and hydrophobic molecules in the same HPLC or LCMS run – Tips & Suggestions Read More →
Use a low concentration of salt in your mobile phase to avoid ion suppression and build up on your inlet source – Tips & Suggestions Read More →
Using ammonium acetate or formate in an acetonitrile based HPLC mobile phase for Aqueous Normal Phase ANP – Tips & Suggestions Read More →
Using ammonium acetate or triethylamine TEA with Cogent HPLC columns – Tips & Suggestions Read More →
Using an Aqueous Normal Phase ANP method will sodium ions interfere with succinate when analyzing sodium succinate – FAQ Read More →
Using triethylamine TEA in Aqueous Normal Phase ANP methods for simple sugars – Tips & Suggestions Read More →
Using two HPLC columns together in a tandem separation for polar and non polar retention – Tips & Suggestions Read More →
What are some notable examples of journal articles that feature Aqueous Normal Phase ANP methods in metabolomics studies – FAQ Read More →
What effect does high injection volume have on column performance in Aqueous Normal Phase ANP HPLC- FAQ Read More →
What is the maximum salt concentration to use with Cogent TYPE-C HPLC columns with HPLC or LCMS – FAQ Read More →
What is the purpose of using isopropanol IPA as part of the mobile phase solvent in ANP methods – FAQ Read More →
What problems can occur when using a dedicated Reversed Phase HPLC instrument for an Aqueous Normal Phase ANP method for the first time – FAQ Read More →
Why am I observing broad split peaks in Aqueous Normal Phase ANP when using acetonitrile and methanol diluents – FAQ Read More →
Why are ionized polar compounds generally better retained in Aqueous Normal Phase ANP HPLC – FAQ Read More →
Why do I have lower than normal back pressure with Cogent Diamond Hydride HPLC columns – FAQ Read More →