Cogent UDA HPLC Column Use – AppNote

Ion exchange chromatography can be a useful tool available to the analytical chemist. In this separation mode, an ionized moiety on the stationary phase interacts electrostatically with an oppositely charged analyte. There are several types of ion exchange that can be used, such as strong anion exchange, weak anion exchange, strong cation exchange, and weak […]

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Ethyl Glucuronide Analysis by HPLC with LCMS – AppNote

Method Optimization in Separation of Ethyl Glucuronide and Ethyl Sulfate Ethyl Glucuronide and Ethyl Sulfate are compounds that are not well-retained or separated using Reversed Phase Columns due to their hydrophilicity thus requiring high water concentrations in the Mobile Phase. To avoid the use of high water content Mobile Phases, HILIC columns were sought as […]

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