How long will it take for chloroform to degrade the plastic safety coating on the mobile phase bottles if the bottle is broken during a fall – FAQ Read More →
How much pressure can the MicroSolv mobile phase bottles withstand without bursting – FAQ Read More →
How to choose a suitable mobile phase additive for negative ionization mode LCMS – Tips & Suggestions Read More →
How to get improved retention and peak shape for glutamine glutamic acid and aspartic acid – Tips & Suggestions Read More →
How to handle sparging stones to avoid contamination of mobile phases – Tips & Suggestions Read More →
How to keep the Cogent Diamond Hydride column clean when using blood as a sample – Tips & Suggestions Read More →
How to prepare 10mM ammonium acetate buffer 90:10 in acetonitrile for HPLC and LCMS – Tips & Suggestions Read More →
How to prepare 16mM ammonium acetate buffer 90:10 in acetonitrile for HPLC – Tips & Suggestions Read More →
If an analyte is only soluble at basic pH can you use a basic mobile phase for my method – FAQ Read More →
Is TFA or formic acid better as an acidic mobile phase additive for Cogent TYPE-C columns – FAQ Read More →
Mobile Phase recommendation Cogent Diamond Hydride columns for use with serum samples in Aqueous Normal Phase LCMS – Tips & Suggestions Read More →
My LCMS source was getting white film on it and at the same time the background noise was very low so is my Diamond Hydride column bleeding packing material – FAQ Read More →
My retention times are changing after storing my buffer and what could be causing this and tips to help avoid issues – FAQ Read More →
Pre mix your diluent and mobile phase in sample preparation for HPLC – Tips & Suggestions Read More →
Restoring the initial results with a method for analyzing AMP ADP ATP UDP and GPT in biological extracts – Tips & Suggestions Read More →
Retention and or peak shape for citric acid has changed compared to data from a previous HPLC run – Tips & Suggestions Read More →
Since Cogent TYPE-C columns can be used in Reversed Phase or Normal Phase what do you suggest to switch these solvent systems which are not miscible – FAQ Read More →
Suggestion for separation of phenylephrine HCl acetaminophen and dextromethorphan – Tips & Suggestions Read More →
The effect of ionic strength of the mobile phase additive for HPLC columns in Aqueous Normal Phase – Tips & Suggestions Read More →
To obtain greater sensitivity than Na adducts for sugars could you add ammonia NH4 instead – FAQ Read More →
Two gradients to use for analysis of hydrophilic and or hydrophobic molecules in the same Aqueous Normal Phase ANP method – Tips & Suggestions Read More →
Type of gradient to use for analysis of hydrophilic and hydrophobic molecules in the same HPLC or LCMS run – Tips & Suggestions Read More →
Use a low concentration of salt in your mobile phase to avoid ion suppression and build up on your inlet source – Tips & Suggestions Read More →
Using ammonium acetate or triethylamine TEA with Cogent HPLC columns – Tips & Suggestions Read More →
Using methanol instead of acetonitrile in an HPLC method should be done with caution – Tips & Suggestions Read More →
Using triethylamine TEA in Aqueous Normal Phase ANP methods for simple sugars – Tips & Suggestions Read More →