Comparing Cetylpyridinium Chloride Adsorption in Glass Autosampler Vials This Study investigated the effect of Analyte loss due to Adsorption by hydroxyl groups (aka Silanols) on the glass surface of Autosampler Vials over Time. It is well known that the surface of standard, including industry leading Borosilicate Glass Vials are populated with Silanols and Basic Analytes […]
Category: AppNotes RSA Vials
Basic Compound Concentration and Adsorption Study in Autosampler Vials – AppNote
Comparing Cetylpyridinium Chloride Adsorption on RSA Glass v. Standard Autosampler Vials In this study, the importance of Analyte Concentration is demonstrated when dealing with Adsorption during analyses of Basic Solutes. Using conventional glass of an industry leading supplier, the basic test analyte Cetylpyridinium Chloride showed notable loss to Adsorption with the Vial at the lower […]
Basic Compound Functional Group Dependent Adsorption Study in Autosampler Vials – AppNote
Adsorption Comparison to Conventional Glass Autosampler Vials. Various test solutes were investigated in this study in order to determine the role that compound specific functional groups play in analyte loss to a Vial. Percent loss increased in order of increasing number of Amine Groups and was greatest with permanently cationic species (Thiamine and Cetylpyridinium Chloride). […]
RSA-Pro X vial improve quantitation precision with HPLC – AppNote
RSA-Pro X™ – Hydrolytically stable hydrophobic glass vials & low volume glass inserts Silanol groups (Si-OH) on the surface of glass has been known to cause not only empirical quantitative loss but also inaccurate quantitation, vial to vial and run to run over time. Silanol sites are very reactive and can produce among other things, […]