This is most likely due to “channeling” of the flow pattern inside the column.
The packed bed uniformity has likely been disrupted and the split peaks and high pressure are indicative of this. In this case, the column will need to be replaced.
This is most likely due to “channeling” of the flow pattern inside the column.
The packed bed uniformity has likely been disrupted and the split peaks and high pressure are indicative of this. In this case, the column will need to be replaced.
