Under normal conditions, yes.
In terms of the performance of this unit, the intended scope of the product is for removal of particulate matter and gas bubbles that can appear in HPLC solvents. The filter membrane that is included for particulates is compatible with most HPLC solvents and the vacuum that is needed for this unit to work, will remove dissolved gases such as oxygen & carbon dioxide from the HPLC solvent. It is important to note that exposure to the atmosphere will re-dissolve gases in the solvents. Not all solutions or solvents will be compatible with this unit.