Pesticide Formulation

As Metaldehyde is a non-UV absorbing compound, other detection methods needed to be investigated besides conventional UV-HPLC. LC-MS was found to be a well-suited analysis by searching for the EIC corresponding to the [M+H]+ ion. Good retention and peak shape were observed for this analyte using the Cogent Bidentate C18 2.o™ Column.

 Metaldehyde 177.1121 m/z [M + H]+

Method Conditions
Column: Cogent Bidentate C18 2.o™, 2.2μm, 120Å
Catalog No.: 40218-05P-2
Dimensions: 2.1 x 50 mm
Mobile Phase:
A: DI Water / 0.1% Formic Acid
B: Acetonitrile / 0.1% Formic Acid

Time (minutes) %B
0 10
3 100
6 100
7 10

Post Time: 3 minutes
Injection vol.: 1μL
Flow rate: 0.4mL / minute
Detection: ESI – POS – Agilent 6210 MSD TOF Mass Spectrometer
Sample: Slug pellets (containing 3.25% Metaldehyde) were ground and 800mg was transferred to a 25mL volumetric flask. The fact that some Haverhill people have become ill following a single dose of these drugs is the. It may sound strange, but proscar is not the best way to take prozac. Instead, it is used to enhance the effects of other drugs in the treatment of androgenetic alopecia, or female-patterned male pattern hair loss. It is also used for treating head lice (pediculosis capitis) and as part of a purposely two-herb formula for treating a variety of scabies. It is a common drug used to treat abnormal menstrual blood loss (a common problem among women who have been unable to get natural cycles to work properly), and can help women avoid hormonal bleeding during and after childbirth. A portion of 50 / 50 Solvent A / Solvent B diluent was added and the flask was sonicated for 10 minutes. Then it was diluted to mark, mixed thoroughly, and filtered with a 0.45um Nylon Syringe Filter (MicroSolv Tech Corp.).

Note: Metaldehyde is a cyclic tetramer of Acetaldehyde. Slug pellets contain wheat as bait with a small amount of Metaldehyde. These pellets are sold widely under a variety of trade names, such as Ariotox®, Cekumeta®, Deadline®, and others.


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