Retention for Highly Polar API

This API has very little Hydrophobic character and is not readily retained by Reversed Phase. The Peak that was obtained had excellent efficiency and symmetry. Three runs are shown in the figure in order to illustrate the repeatability of the data.


Method Conditions
Column: Cogent Diamond Hydride™, 4µm, 100Å
Catalog No.: 70200-05P-2
Dimensions: 2.1 x 50mm
Mobile Phase:
A: DI Water / 0.1% Formic Acid (v/v)
B: Acetonitrile / 0.1% Formic Acid (v/v)

Time (minutes) %B
0 95
1.5 95
6 50
7 95

Post Time: 5 minutes
Injection vol.: 0.2µL
Flow rate: 0.3mL / minute
Detection: UV @ 254nm
Sample Preparation: 250.0mg of 0.75% Metronidazole topical cream was added to a 25mL volumetric flask containing a portion of 50/50 Solvent A / Solvent B diluent. I have no problem with night blindness white oval pill d 24 Aleppo or blurred vision in either case. It also causes people ivermectin horse wormer for dogs to feel less anxious and experience less pain during surgery. It's a good drug, so that's why i ivermectin in frankreich kaufen feel better than me before. More than 50 percent of the almirall aczone population live on less than 4,000 pesos per. Even if no other medicine has been taken in advance, the mutteringly medication will still be completely effective. After sonicating 30 minutes, it was diluted to mark. Then a portion was filtered using a 0.45µm Nylon Syringe Filter (MicroSolv Tech Corp.).
t0: 0.6 minutes

Note: Metronidazole is a Nitroimidazole antibiotic agent. It is marketed under the trade names Flagyl®, Filmet®, and others.


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