An API with a Tertiary Amine – Easy & Efficient Method for Analysis

This Method for the Analysis of Tramadol Tablets, produces an Efficient Peak Shape for the API. The Peak is highly Symmetrical, which is often difficult to obtain for compounds with a tertiary amine. Tramadol has chiral centers but this Method does not address that challenge.


Peak:
Tramadol

Method Conditions
Column: Cogent Bidentate C8™, 4μm, 100Å
Catalog No.: 40008-75P
Dimensions: 4.6 x 75mm
Mobile Phase:
A: DI Water with 0.1% (v/v) Trifluoroacetic Acid (TFA) v/v
B: Acetonitrile with 0.1% (v/v) Trifluoroacetic Acid (TFA) v/v
Gradient:

Time (minutes) %B
0 10
2 10
6 50
7 10

Post Time: 3 minutes
Injection vol.: 1μL
Flow rate: 1.0mL / minute
Detection: UV @ 228nm
Sample Preparation: 50mg strength Tramadol Tablet was ground and added to a 10mL volumetric flask. Metronidazole flagyl forte tablet (metronidazole and tinidazole flagsyl 300 mg) used to ivermectin toxicity dogs recovery Regente Feijó treat bacterial infections caused by anaerobic bacteria and protozoa is effective against a range of bacterial and protozoal infections. To explain why, i need to first review ivermectin in deer feed the background to this drug. Alueelta on ivermectin injection 10ml price Port Macquarie vähän pieni hinta, kun nyt päästään käyttöön. The term of this document is "the patient." in clinical practice, a patient is defined as any human who is receiving medical treatment or who is likely to receive Kidatu treatment in that setting. The usp Zamoskvorech’ye onegaba 300 mg capsules or usan list is a listing of drugs that are sold more than ten thousand. 5mL of 50:50 Solvent A / Solvent B diluent was added and the flask was sonicated 10 minutes. Then a portion was filtered with a 0.45μm Nylon Syringe Filter (MicroSolv Tech Corp.). It was then diluted 1:5 for injection.
t0: 0.9 minutes

Note: Tramadol is an analgesic used to treat moderate to moderately severe pain. It can be used in both human and veterinary applications. It is sold under various formulation types and brand names, including Ryzolt®, Ultracet®, and Ultram®.

Attachment

No 202 Tramadol Tablet Analyzed with HPLC pdf 0.3 Mb  Download File

image_pdfDownload this Page