What is the highest amount of vacuum pressure that I can safely apply to the 0.45 µm nylon filter membranes disc without them bursting?

Although the burst pressure for nylon membranes of this nature is approximately 80 psi (5.5 bar), we suggest not to exceed 50 psi (3.45 bar). Typical vacuum pressure for mobile phase filtration is approximately 30 psi (2 bar).

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