Which column coupler do you recommend for pairing HPLC columns with guard columns- Tech Information

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ARTICLES, APPNOTES, FAQ (9292)
- AppNotes Library (1888)
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May 9, 2023
Tanya

ARTICLES, APPNOTES, FAQ / Chromatography Accessories & Supplies Information / Column Couplers / Equipment FAQ / Fittings Connectors Nuts Ferrules Information / Frequently Asked Questions?? / Sample Loops / Tools Information / Tubing Information / Unions

The ARE-Applied Research™ brand of column couplers are used to connect the flow of two HPLC columns or a guard column and an analytical column directly in series.

Below is our recommended selection chart to match your flow rate and a suggested union-column coupler (ID). The ID of the coupler should be determined based on your application, where the faster the flow, the larger the bore (ID) is needed.

Flow rate (milliliters / minute)	Through Hole (mm)	Through Hole (inch)	Column Coupler Cat. No.
up to 0.5	0.13	0.005	47450-01
≤1.0	0.18	0.007	47450-02
1.0 – 2.0	0.25	0.010	47450-03
≥2.0	0.50	0.020	47450-04

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1) Can the Cogent Column Filters replace my HPLC guard columns – FAQ

2) How do I connect a guard column to an analytical column – FAQ

3) Choose an appropriate guard column when using a Cogent TYPE-C HPLC column – How To

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