Valganciclovir Hydrochloride USP assay with HPLC – AppNote

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ARTICLES, APPNOTES, FAQ (9292)
- AppNotes Library (1888)
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September 15, 2022
Tanya

AppNotes Alternate Generic Methods / AppNotes Library / AppNotes Listed by Column / AppNotes Pharmaceuticals / AppNotes Reversed Phase Methods / AppNotes RP C18

Alternate column used for a USP assay method of Valganciclovir Hydrochloride

This similar column for use in analyzing USP Valganciclovir Hydrochloride is easily performed, and the 10 injections overlay below demonstrates run to run consistency and great peak symmetry. The peak efficiency is very good and peak tailing guidelines are easily met with RSD values of less than 1.0%.

This demonstrates a good alternate column for your Valganciclovir Hydrochloride USP method.

Peak:

Diastereomers Valganciclovir Hydrochloride

Method Conditions:
Column: Cogent RP C18™, 5um, 100Å
Catalog No.: 68518-15P
Dimensions: 4.6mm x 150mm

Note 1: For the full method conditions and details, consult the official United States Pharmacopeia–National Formulary (USP–NF.)
Note 2: Valganciclovir Hydrochloride is an antiviral prescription medicine for the treatment of cytomegalovirus retinitis (CMV retinitis) in adults with AIDS. It is also used for the prevention of CMV disease in recipients of organ transplants who are at risk for CMV diseases.

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