Carboplatin USP assay with HPLC – AppNote – MicroSolv Technology Corporation

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ARTICLES, APPNOTES, FAQ (9187)
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June 21, 2022
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AppNotes Alternate Generic Methods / AppNotes Cogent RP C8 / AppNotes Library / AppNotes Listed by Column / AppNotes Pharmaceuticals / AppNotes Reversed Phase Methods / ARTICLES, APPNOTES, FAQ

Alternate L8 column used for a similar USP assay method of Carboplatin

This similar USP Carboplatin assay is easily performed and the 10 injections overlay below demonstrates run to run consistency and great peak symmetry. The peak efficiency is very good and peak tailing guidelines are easily met with RSD values of less than 1.0%.

This demonstrates a good alternate column for your Carboplatin USP method.

Peak:

Carboplatin

Method Conditions:
Column: Cogent NP Amino™, 5um, 100Å
Catalog No.: 68540-15P
Dimensions: 4.6mm x 150mm

Note 1: For the full method conditions and details, consult the official United States Pharmacopeia–National Formulary (USP–NF.)
Note 2: Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.

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