What are the advantages and disadvantages of acid washing RSA vials – FAQ

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ARTICLES, APPNOTES, FAQ (9292)
- AppNotes Library (1888)
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June 19, 2018
Bill Ciccone

ARTICLES, APPNOTES, FAQ / Autosampler Vials Information / Crimp Top Vials & Cap FAQ / Headspace Vial FAQ / HPLC & GC Standard Vials Caps & Inserts / HPLC Suggestions and Information / HPLC Tips and Suggestions / Inserts FAQ / MicroSolv Autosampler Vials FAQ / RSA Vials FAQ / U-2D Sample MGT FAQ / Vials & Caps General FAQ

Acid washing autosampler vials has consequences.

There is no reason to acid wash RSA vials. The main reason to wash ordinary vials is to reduce adsorption due to native silanols on the glass. Since RSA has virtually no silanols, this is not necessary.

Some of the consequences to acid washing include time and materials but also you run the risk of chloride and sodium residue left in the vials as well as other trace elements found in the reagents.

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