The maximum pressure is the same as the analytical columns. The standard 4um columns are rated up to 6000 psi but no more than 4500 psi is recommended during the run. The 2.o™ phases are suggested at no more than 9000 psi. 

A PEEK column coupler will suffice unless you are using UHPLC, which is not recommended.

Click HERE for Ordering Information that includes Column Couplers