Separation from matrix peaks

Lansoprazole is separated from several Matrix Components in this simple assay method. The Mobile Phase is LC-MS compatible so the method could be applied to more complex samples such as plasma. Five runs are shown in the figure to illustrate the repeatability of the data.


Method Conditions
Column: Cogent Bidentate C18™, 2.2µm, 120Å
Catalog No.: 40218-05P-2
Dimensions: 2.1 x 50 mm
Mobile Phase:
A: DI Water / 0.1% Formic Acid (v/v)
B: Acetonitrile / 0.1% Formic Acid (v/v)

Time (minutes) %B
0 10
1 10
6 70
7 10

Injection vol.: 0.2 μL
Flow rate: 0.4mL / minute
Detection: UV @ 285 nm
Sample Preparation: 15mg strength Lansoprazole capsule contents were ground and added to a 25mL volumetric flask. The drug is a proton pump inhibitor that reduces acid secretion in the stomach and small intestines that can slow the growth of helicobacter ivermectin pills humans pylori infection. These individuals have significant disability, reduced quality of life, and a high cost for hospitalization and outpatient care. It is also a good idea to take a look at the terms Kandukūr ivermectin for ticks on dogs and conditions on the product’s website to make sure you have the correct information about delivery and postage. This is a very difficult question that whiles i have been debating for years. If you are following a course of high-dose steroid treatment for an autoimmune condition in Kaltan ivermectin costs pregnancy, your health should be monitored closely and you should discuss your pregnancy care with your gp or nurse before the treatment begins. A portion of 50/50 Solvent A / Solvent B was added and the flask was sonicated 10 minutes. Then it was diluted to mark and mixed. A portion was filtered through a 0.45µm Nylon Syringe Filter (MicroSolv Tech Corp.).
t00.5 minutes

Note: Lansoprazole is a proton-pump inhibitor used for acid reducing effects. It is available over-the-counter by Novartis under the trade name Prevacid, as well as generic versions.


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