What is the structure of the Cogent Phenyl Hydride bonded ligand – FAQ

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ARTICLES, APPNOTES, FAQ (9292)
- AppNotes Library (1888)
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December 4, 2012
Bill Ciccone

ARTICLES, APPNOTES, FAQ / Cogent Phenyl Hydride Information / HPLC Column Information / Phenyl Hydride FAQ / TYPE-C Column Information / TYPE-C in General FAQ

The Cogent Phenyl Hydride phase is a 4 carbon chain with a phenyl group at the end attached directly to the silica hydride surface with a single, direct silicon-carbon bond.

With bonds in traditional silica B based materials, the organo-silane starting material is Si-O-Si-C4-Phenyl and this reagent is reacted with the silica to form the final stationary phase which includes a Si-O-Si-C4-Phenyl ligand.

This is in contrast with the TYPE-C phases in that the Si-C bond is formed directly as part of the reaction resulting in Si-C4-Phenyl without the oxygen in the link which is very susceptible to hydrolysis.

More information on Phenyl Hydride HPLC Columns

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