No, the pre-column, Cogent Column Filter is completely compatible with all 1/16th”, 10-32 internal fitting ports. Most modern brands of HPLC columns are fully compatible.
Finger tighten the filters right into the inlet side of the guard or analytical column (universal fit) and a finger tight male nut to hold your stainless or PEEK tubing inserted into the inlet side of the filter. Add 1/8 of a turn once you feel the filter is fairly tightly installed for the best seal.