No impact at all.

There will certainly be mobile phase preparation differences, aging of columns, etc. The HSQ Kit™ instructions call for adjustment of the mobile phase to meet system suitability, which for example in our C of A, calls to adjust the mobile phase to achieve a 4-5 minute retention time window. Keep in mind that the C o A merely confirms that the column was tested, and met specs when it left our facility.

Click HERE for PQ and HSQ Kit ordering information and pictures.