How long will it take for chloroform to degrade the plastic safety coating on the mobile phase bottles if the bottle is broken during a fall – FAQ

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ARTICLES, APPNOTES, FAQ (9292)
- AppNotes Library (1888)
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April 2, 2012
Bill Ciccone

ARTICLES, APPNOTES, FAQ / Chromatography Accessories & Supplies Information / Frequently Asked Questions?? / HPLC Suggestions and Information / HPLC Tips and Suggestions / Mobile Phase Bottle Information / Mobile Phase FAQ / Mobile Phase Suggestions / Tips Liquid Handling

This is a difficult question to answer as it also depends on the severity of the impact suffered by the bottle:

If the glass is just cracked it may take time (minutes to hours) for the chloroform to seep through the cracks and dissolve the polyurethane. Whereas if the impact was so severe that glass fragments were detached from the polyurethane coating, the chloroform would be immediately in direct contact with the polyurethane.

Polyurethane is highly soluble in chloroform; so once chloroform is in direct contact; it will dissolve the bottle coating in approximately 10 – 30 seconds.

Click HERE for safety coated mobile phase bottle ordering information and pictures.

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