Can I use Silica C columns in a Normal Phase gradient method – FAQ

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ARTICLES, APPNOTES, FAQ (9012)
- AppNotes Library (1878)
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April 2, 2012
Bill Ciccone

ARTICLES, APPNOTES, FAQ / Cogent Silica-C Information / HPLC Column Information / Silica-C FAQ / TYPE-C Column Information

Yes!

Although this is not easy with ordinary silica columns due to solvent de-mixing & water uptake, the Cogent Silica-C™ column is not limited by this and is easy to use even with fast gradients.

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