There are many reasons to use Cogent TYPE-C columns for new methods. Below are some of the reasons and attached is a White Paper that provides a concise argument.
Often gradients are required to cope with large differences in polarity of multiple compounds in a mixture. With TYPE-C™ columns there always is the possibility to achieve isocratic analyses where traditional HPLC Columns could require gradients. As can be seen from a real life examples Cogent TYPE-C™ columns also have the ability to retain compounds that cannot be retained on previous types of supports and phases.
Also, the lack of water retention on Cogent TYPE-C™ columns makes change of pH and switching between aqueous reverse/normal phase to organic normal phase rapid and memory free. TYPE-C™ columns have multiple separation mechanisms at work, which can be modified by choice of appropriate bonded phase to interact or act separately. Unique but predictable separations can be extrapolated from retention maps
The most popular reason is the increased selectivity power of these columns and the ability to be orthogonal to themselves. For untargeted analysis, these columns have no equal for this reason.
Why Labs Should Adopt TC.pdf 52.2 Kb Download File