Furazolidone Analyzed with HPLC – AppNote – MicroSolv Technology Corporation

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ARTICLES, APPNOTES, FAQ (9292)
- AppNotes Library (1888)
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May 11, 2012
Bill Ciccone

AppNotes Cogent Bidentate C18 / AppNotes Library / AppNotes Pharmaceuticals / AppNotes Reversed Phase Methods / ARTICLES, APPNOTES, FAQ

API and Related Compounds Separation

Furazolidone was Separated from related compounds in a commercially available pharmaceutical preparation. Excellent Peak shape and Selectivity from the related compounds was achieved with this Robust Method making it a great choice for QC applications even when using aggressive Mobile Phases that include acids. Molecular weight of Furazolidone is 225.16.

Peak:
Furazolidone

Method Conditions
Column: Cogent Bidentate C18™, 4µm, 100Å
Catalog No.: 40018-15P
Dimensions: 4.6 x 150mm
Mobile Phase: 12% Acetonitrile / 88% DI Water / 1% Acetic Acid
Temperature: 30°C
Injection vol.: 20µL
Flow rate: 2mL / minute
Detection: UV @ 365nm

Note: This antibiotic drug is used to treat diarrhea and enteritis caused by bacteria or protozoan infection. Also used as a veterinary medicine for salmonids and Myxobolus cerebralis infection.

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