Can I use ion pairing reagents with the Cogent Diamond Hydride HPLC column – FAQ

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ARTICLES, APPNOTES, FAQ (9292)
- AppNotes Library (1888)
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April 25, 2018
Bill Ciccone

ARTICLES, APPNOTES, FAQ / Cogent Diamond Hydride Information / Diamond Hydride FAQ / HPLC Column Information / HPLC Tips and Suggestions / Mobile Phase Suggestions / Trouble Shooting Suggestions / TYPE-C Column Information

Ion-pairing will not work with the Diamond Hydride column.

It separates compounds on the basis of polarity. Using an ion-pairing reagent reduces that polarity so the compound can be separated on a Reversed Phase column.

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