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L(+)-a-phenylglycine Antibiotic Analysis

Reference Number: AA-00772 Created: 05/16/2012 06:36 AM Last Updated: 07/12/2013 10:32 AM

Using Cogent Silica-C™ column 

Discussion


Cogent Silica-C column produces satisfactory retention of the important amino acid L(+)-a-phenylglycine under isocratic elution using a simple mobile phase. In addition the retention when using the Cogent Silica-C column is extremely reproducible (%RSD 0.2).

Phenylglycine is a synthetic amino acid used in manufacturing lactam antibiotics, such as semi-synthetic cephalosporines and penicillins. The application above is done using the ANP (aqueous normal phase) mode.
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No 46 Amino Acid PhenylGlycyne Silica-C.pdf 0.4 Mb Download File
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