Why am I seeing two peaks for quaternium15 Dowicil-75 in LCMS - FAQ
September 25, 2014
/
/
/
/
/
/
/
/
/
/
Question: I am using LC-MS and the Cogent Diamond Hydride™ HPLC column. When analyzing quaternium-15 sold as Dowicil-75™ , I see two peaks which have the same m/z. What can be the cause? Is there an issue of peak splitting?



Answer: Quaternium-15 can have either cis or trans orientation on the double bond. If you see two peaks in your data, it may not be from peak splitting but rather chromatographic separation of the two isomers.

Click HERE for Cogent Diamond Hydride™ ordering information

Related Articles

  1. Cefprozil E & Z Isomers Analyzed with HPLC - AppNote
  2. Eliminate broad split peaks in Aqueous Normal Phase ANP methods and a methanol diluent- Tips & Suggestions
  3. Types of isomers and suitable HPLC columns for separation - Tips & Suggestions

© Copyright 2025. MICROSOLV. All Rights Reserved. Website & Hosting by BlueTone Media