Category: TYPE-C Column Information
/
/
/
A white film developed on my MS source so is this column packing material - FAQ
Read More
Amide or amino HPLC columns. - Tech Information
Read More
Analyte retention decreases with mobile phase water content using the Cogent Bidentate C18 HPLC column has anything happened to the column - Tech Information
Read More
Analyze phosphorylated compounds with the Cogent Diamond Hydride column - Tips & Suggestions
Read More
Aqueous Normal Phase ANP and how can it is useful for polar compounds - Tech Information
Read More
Aqueous Normal Phase ANP ballistic gradients compared to same in HILIC - Tips & Suggestions
Read More
Aqueous Normal Phase ANP defined & compared to Reversed Phase & Normal Phase definitions HPLC
Read More
Aqueous Normal Phase ANP HPLC retention mechanism elucidated - Tech Information
Read More
Aqueous Normal Phase ANP HPLC what is it - FAQ
Read More
Aqueous Normal Phase ANP solvent strength order - FAQ
Read More
Are Cogent 2.o HPLC columns compatible with Agilent 1290 Infinity II instruments - FAQ
Read More
Are Cogent TYPE-C silica 2.o columns considered UHPLC phases - FAQ
Read More
Are Cogent TYPE-C Silica columns made with hybrid particles - FAQ
Read More
Are the Cogent TYPE-C Silica based stationary phases available for sale as bulk materials - FAQ
Read More
Are there HPLC columns that could be used to separate both polar and nonpolar compounds in a single run - FAQ
Read More
Assuring retention of polar compounds in an Aqueous Normal Phase ANP gradient in positive ion mode LCMS - Tips & Suggestions
Read More
Better methods than HILIC in HPLC and LCMS - Tips & Suggestions
Read More
Biological extracts Diamond Hydride columns and LCMS ion source diminished peak height problem - FAQ
Read More
Blocked HPLC column from proteins from the sample matrix can be recovered - Tips & Suggestions
Read More
Buffer concentration can affect ANP retention of acids in HPLC Analyses - Tips & Suggestions
Read More
Calculate the ligand density of a bonded phase of an HPLC column - How To
Read More
Can Aqueous Normal Phase ANP methods be used to separate steroids - FAQ
Read More
Can Cogent TYPE-C HPLC columns be used in supercritical fluid chromatography SFC - FAQ
Read More
Can I expect a more predictable retention time with Silica-C columns than with ordinary silica - FAQ
Read More
Can I use a silica or Silica-C guard column with an analytical column of a different phase - FAQ
Read More
Can I use Acetone as a mobile phase solvent in Aqueous Normal Phase ANP - FAQ
Read More
Can I use ion pairing reagents with the Cogent Diamond Hydride HPLC column - FAQ
Read More
Can I use of the Cogent Diamond Hydride HPLC column above pH 7 in HPLC - FAQ
Read More
Can I use phosphoric acid or sodium phosphate with the Cogent Diamond Hydride HPLC column - FAQ
Read More
Can I use Silica C columns in a Normal Phase gradient method - FAQ
Read More
Can I use the Cogent Diamond Hydride column without mobile phase additives like formic acid - FAQ
Read More
Can I use triethylamine TEA with a Cogent Silica-C column - FAQ
Read More
Can I use triethylamine TEA with Cogent Diamond Hydride columns - FAQ
Read More
Causes of high baseline noise with Cogent Diamond Hydride HPLC column - Tips & Suggestions
Read More
Changing column ID means changing your gradient - Tips & Suggestions
Read More
Changing retention times of amino acids in biological extracts using ammonium acetate in HPLC methods. - Troubleshooting.
Read More
Choose an appropriate guard column when using a Cogent TYPE-C HPLC column - How To
Read More
Cleaning Cogent TYPE-C silica based HPLC columns - Tips & Suggestions
Read More
Cogent Diamond Hydride 2.o HPLC column retention time precision - AppNote
Read More
Cogent silica hydride HPLC columns by order of hydrophobicity - Tips & Suggestions
Read More
Cogent TYPE-C column end fitting hardware and dimensions - Tips & Suggestions
Read More
Cogent TYPE-C columns used in prep chromatography offer value - Tips & Suggestions
Read More
Cogent UDA HPLC Column Use - Extended AppNote
Read More
Convert HPLC columns between Reversed Phase and Normal Phase - How to
Read More
Determine pore volume of an HPLC column using HPLC injections - How To
Read More
Determining Efficiency of HPLC methods comparing 4um v 2.o HPLC columns - Tips & Suggestions
Read More
Developing a Bromhexine HPLC method - Tips & Suggestions
Read More
Direct silicon to carbon bonds on Cogent TYPE-C HPLC columns produce longer column lifetimes
Read More
Do Tanaka Plots for HPLC apply to columns used with Aqueous Normal Phase ANP methods - FAQ
Read More
Do the Cogent Silica-C columns contain any carbon - FAQ
Read More
Eliminate broad split peaks in Aqueous Normal Phase ANP methods and a methanol diluent- Tips & Suggestions
Read More
For the separation of polar intermediates in reversed phase HPLC which C18 column do you recommend - FAQ
Read More
Fosetyl Aluminum analysis by HPLC - Tips & Suggestions
Read More
Fosetyl aluminum analysis by Reversed Phase HPLC - Tips & Suggestions
Read More
Glucose pyruvate taurocholic acid gamma glutamylcysteine and other analysis - Tips & Suggestions
Read More
Helpful HPLC columns you may not know about - White Paper
Read More
High molecular weight compounds that won't retain on Cogent Diamond Hydride column try Cogent Bidentate C8 300 - Tips & Suggestions
Read More
High pressure develops after flushing a Cogent Diamond Hydride column with acetonitrile cause and solution - FAQ
Read More
How a pulse from an HPLC pump affect the column and its performance - Tech Information
Read More
How can Cogent TYPE-C HPLC columns offer faster results compared to other type of silica based columns - FAQ
Read More
How can I get separation of tartaric and malic acid in a complex mixture? - FAQ.
Read More
How can I improve accuracy and precision when separating polar compounds by HPLC using Aqueous Normal Phase ANP - FAQ
Read More
How can I restore my Diamond Hydride HPLC column after I ran out of mobile phase and air was accidently introduced into it - FAQ
Read More
How can I separate capsaicinoids in hot sauce by HPLC - Tips & Suggestions
Read More
How can I separate methacrylic acid and dodecyl benzene sulfonic acid - FAQ
Read More
How do I avoid distorted peak shapes when using a basic mobile phase pH for the analysis of a lipophilic amine - FAQ
Read More
How do I connect a guard column to an analytical column - FAQ
Read More
How do the terms nano capillary and micro LC differ in terms of column ID and typical flow rates - FAQ
Read More
How does ammonium fluoride affect chromatography using Cogent TYPE-C HPLC columns?
Read More
How does ammonium fluoride affect HPLC and LCMS data if using Aqueous Normal Phase ANP methods - FAQ
Read More
How does efficiency in Aqueous Normal Phase ANP compare to HILIC in HPLC - FAQ
Read More
How does the Cogent UDA HPLC column's ligand bond to the silica hydride surface - FAQ
Read More
How often do I need to clean or wash a Cogent TYPE-C column to keep data precise - FAQ
Read More
How often do I need to do the conditioning procedure for a new Diamond Hydride column - FAQ
Read More
How to back flush and wash an HPLC column for reuse - Tips & Suggestions
Read More
How to choose a suitable mobile phase additive for negative ionization mode LCMS - Tips & Suggestions
Read More
How to determine concentration of an impurity in HPLC with the relative response factor RRF - How to
Read More
How to eliminate retention time drift in LCMS with Aqueous Normal Phase ANP methods - Tips & Suggestions
Read More
How to fix a saw tooth pattern in the UV baseline - Tips & Suggestions
Read More
How to get improved retention and peak shape for glutamine glutamic acid and aspartic acid - Tips & Suggestions
Read More
How to improve LOD or detection limits in HPLC - Tips & Suggestions
Read More
How to improve peak shapes, retention & carryover for polar compounds with the Cogent Diamond Hydride™ column - Tips & Suggestions
Read More
How to keep the Cogent Diamond Hydride column clean when using blood as a sample - Tips & Suggestions
Read More
How to separate phospholipids with HPLC - Tips & Suggestions
Read More
I am not observing any peaks for succinic acid or alpha-ketoglutarate with the Cogent Diamond Hydride column - Tips & Suggestions
Read More
I heard that there is not a good alternative to HILIC to achieve sufficient retention for some compounds - FAQ
Read More
I see a strange saw tooth type of pattern in the UV baseline using my Cogent HPLC column what is it and how can I fix it - FAQ
Read More
Improvement in signal to noise in LCMS with an ANP method - Tips & Suggestions
Read More
Injection Technique for Aqueous Samples using Cogent TYPE-C Columns in ANP - Tips & Suggestions
Read More
Is TFA or formic acid better as an acidic mobile phase additive for Cogent TYPE-C columns - FAQ
Read More
Is the Cogent UDC Cholesterol HPLC column stable as a stationary phase - FAQ
Read More
Is TYPE-C Silica a high purity support and have a low metal content silica like Type B silica - FAQ
Read More
Issues arising from changes in mobile phase with acids to one with ammonium salts. Tips & Suggestions
Read More
LFER studies compared to Log D data in describing the Aqueous Normal Phase ANP retention - Tips & Suggestions
Read More
Literature references for Cogent TYPE-C HPLC columns - Tech Information
Read More
Lower retention is observed when functional group in a compound is ionized - Tips & Suggestions
Read More
Method development tip for maleic hydrazide - Tips & Suggestions
Read More
Mobile Phase recommendation Cogent Diamond Hydride columns for use with serum samples in Aqueous Normal Phase LCMS - Tips & Suggestions
Read More
Modify selectivity in an ANP method of HPLC using different mobile phase pH - Tips & Suggestions
Read More
My LCMS source was getting white film on it and at the same time the background noise was very low so is my Diamond Hydride column bleeding packing material - FAQ
Read More
My method uses an standard type-B silica based HPLC column is there a Cogent TYPE-C column equivalent substitute - FAQ
Read More
Negative Baselines in HPLC at 214nm - Tips & Suggestions
Read More
NMR structure confirmation data for Cogent Bidentate C18 phases - Tech Information
Read More
NMR structure confirmation data for Cogent Bidentate C8 phases - Tech Information
Read More
NMR structure confirmation data for Cogent UDC-cholesterol phases - Tech Information
Read More
No need to use a high pH mobile phases for compounds with a high pKa - Tips & Suggestions
Read More
Obtain a flat baseline in a gradient method without using blank subtraction - How to
Read More
Peak area decreases with increasing flow rate - FAQ
Read More
Percentage of acid needed in Aqueous Normal Phase ANP methods - Tips & Suggestions
Read More
pK of common chemical functional groups in HPLC - FAQ
Read More
Polar and non polar peptides analyzed by LCMS with an Aqueous Normal Phase ANP method - Tips & Suggestions
Read More
Policy on verifying a new Cogent HPLC column performance - Tips & Suggestions
Read More
Poor HPLC peak shape can be due to injection sample mismatch - Tips & Suggestions
Read More
Precision and suitability of the Cogent TYPE-C Silica HPLC columns in LC-MS
Read More
Purge metals from HPLC system using EDTA or medronic acid - How To
Read More
Restoring the initial results with a method for analyzing AMP ADP ATP UDP and GPT in biological extracts - Tips & Suggestions
Read More
Retention and or peak shape for citric acid has changed compared to data from a previous HPLC run - Tips & Suggestions
Read More
Retention time varies from instrument to instrument - Tips & Suggestions
Read More
Sample concentration changes can effect retention time in HPLC - Primer
Read More
Since Cogent TYPE-C columns can be used in Reversed Phase or Normal Phase what do you suggest to switch these solvent systems which are not miscible - FAQ
Read More
Since Cogent TYPE-C Silica columns use a transition metal catalyst in production what is the presence of any trace quantity on the surface of the stationary phase- FAQ
Read More
Solving baseline problems in ANP methods with the Cogent Diamond Hydride column - Tips & Suggestions
Read More
Solving baseline problems in Aqueous Normal Phase ANP methods - Tips & Suggestions
Read More
Specifications of different grades of stainless steel used in HPLC columns
Read More
Store and condition Cogent TYPE-C HPLC columns - How To
Read More
Store and maintain Cogent Diamond Hydride HPLC columns - How To
Read More
Suggestion for separation of phenylephrine HCl acetaminophen and dextromethorphan - Tips & Suggestions
Read More
Suggestions for HPLC method development with silica hydride columns - Tips & Suggestions
Read More
Suggestions on how to separate capsaicinoids in hot sauce by HPLC - Tips & Suggestions
Read More
Tandem LCMS approach to metabolite profiling - AppNote Poster
Read More
Tip for working with plasma samples and Cogent TYPE-C HPLC columns - Tips & Suggestions
Read More
Troubleshooting problems with poor HPLC runs before the examining the column - Tips & Suggestions
Read More
Two gradients to use for analysis of hydrophilic and or hydrophobic molecules in the same Aqueous Normal Phase ANP method - Tips & Suggestions
Read More
Type of gradient to use for analysis of hydrophilic and hydrophobic molecules in the same HPLC or LCMS run - Tips & Suggestions
Read More
Types of isomers and suitable HPLC columns for separation - Tips & Suggestions
Read More
Understanding some of the differences between HILIC columns and TYPE-C columns - Tips & Suggestions
Read More
Use a Cogent TYPE-C column to develop new methods - Tips & Suggestions
Read More
Use a low concentration of salt in your mobile phase to avoid ion suppression and build up on your inlet source - Tips & Suggestions
Read More
Using ammonium acetate or triethylamine TEA with Cogent HPLC columns - Tips & Suggestions
Read More
Using Aqueous Normal Phase ANP to your advantage - White Paper
Read More
Using inorganic buffers for HPLC UV analysis of citric acid - Tips & Suggestions
Read More
Using methanol instead of acetonitrile in an HPLC method should be done with caution - Tips & Suggestions
Read More
Using temperature changes for separations of terpenoids with the Cogent Bidentate C18 and UDC-Cholesterol HPLC columns - Tips & Suggestions
Read More
Using triethylamine TEA in Aqueous Normal Phase ANP methods for simple sugars - Tips & Suggestions
Read More
Using two HPLC columns together in a tandem separation for polar and non polar retention - Tips & Suggestions
Read More
What are some notable examples of journal articles that feature Aqueous Normal Phase ANP methods in metabolomics studies - FAQ
Read More
What are some of the advantages of using Cogent TYPE-C prep and semi-prep HPLC columns - FAQ
Read More
What are the main differences between Cogent Amide columns and other brands of Amide - FAQ
Read More
What are the metal contents of the silica used in Cogent TYPE-C HPLC columns - FAQ
Read More
What are the typical flow rates recommended by HPLC column companies to start with for various column ID - Primer
Read More
What are the uses of PEEK HPLC column hardware - FAQ
Read More
What can cause changing retention times and a peak showing up in my blank with a Silica-C column - FAQ
Read More
What column changes are permitted in USP HPLC methods - FAQ
Read More
What do You suggest for an internal standard in glucosamine LCMS Analysis - FAQ
Read More
What does Post Time mean in an LCMS or HPLC gradient method - FAQ
Read More
What does the term Activity refer to in chromatography - FAQ
Read More
What effect does high injection volume have on column performance in Aqueous Normal Phase ANP HPLC- FAQ
Read More
What is a base deactivated HPLC Column - FAQ
Read More
What is a direct silicon to carbon bond regarding Cogent HPLC columns - FAQ
Read More
What is a master batch for Cogent HPLC columns - FAQ
Read More
What is sample degradation due to hydrolysis in HPLC columns - FAQ
Read More
What is the biggest difference between traditional HPLC phases and Bidentate C18 - FAQ
Read More
What is the Bubbling or Fizzing Coming from a New Cogent TYPE-C Column? - FAQ
Read More
What is the carbon load of the Cogent Diamond Hydride HPLC column - FAQ
Read More
What is the chemical structure of the ligand in the Cogent DIOL HPLC stationary phase - FAQ
Read More
What is the compatibility of Cogent TYPE-C Silica HPLC columns with UHPLC instruments - FAQ
Read More
What is the difference between a 4um and a 5um particle in a C18 column - FAQ
Read More
What is the largest Internal Diameter for Cogent TYPE-C prep columns - FAQ
Read More
What is the maximum loading capacity mass injection volume that can be used for a semi prep Cogent TYPE-C HPLC column - FAQ
Read More
What is the maximum pressure Cogent HPLC columns can tolerate - FAQ
Read More
What is the maximum pressure of your guard columns - FAQ
Read More
What is the maximum salt concentration to use with Cogent TYPE-C HPLC columns with HPLC or LCMS - FAQ
Read More
What is the maximum temperature for Cogent Diamond Hydride HPLC columns - FAQ
Read More
What is the most effective way to clean HPLC columns after or before use - Tips & Suggestions
Read More
What is the pilot length or dimension X depth for end fittings uses to connect HPLC columns - FAQ
Read More
What is the purpose of back flushing an HPLC column and will it damage it - FAQ
Read More
What is the purpose of different bonded phases using Cogent TYPE-C Silica - FAQ
Read More
What is the purpose of using isopropanol IPA as part of the mobile phase solvent in ANP methods - FAQ
Read More
What is the recommended pH range for Cogent Diamond Hydride HPLC columns - FAQ
Read More
What is the structure of the Cogent Phenyl Hydride bonded ligand - FAQ
Read More
What is the volume of Cogent HPLC columns - FAQ
Read More
What pressure should I expect with a Diamond Hydride 2.o HPLC column at flow rates from 0.2 to 2.0mL / min - FAQ
Read More
What type of fitting is best to use with the Cogent HPLC and LCMS columns - FAQ
Read More
What will the pressure be with a mobile phase of 90% methanol and 10% DI water with a 4.6 x 250mm Cogent TYPE-C HPLC column - FAQ
Read More
When is the acid group of the Cogent UDA HPLC column ionized - Tech Information
Read More
Which acid or base additive should I choose for positive or negative ion mode in LC-MS - FAQ
Read More
Which Cogent TYPE-C column do you recommend for the separation of positional isomers by HPLC or LCMS - FAQ
Read More
Which column do you suggest for Cocaine & metabolite Ecognin separation - Tips & Suggestions
Read More
Which HPLC column do you suggest for analysis of carotene or lycopene - FAQ
Read More
Which HPLC column internal diameter should I use for LCMS - FAQ
Read More
Which size guard column should I use with my 1mm Cogent 2.o column - FAQ
Read More
Why am I observing broad split peaks in Aqueous Normal Phase ANP when using acetonitrile and methanol diluents - FAQ
Read More
Why am I seeing two peaks for quaternium15 Dowicil-75 in LCMS - FAQ
Read More
Why am I seeing two peaks for quaternium-15 or Dowicil-75 in my LCMS data - FAQ
Read More
Why are Aqueous Normal Phase ANP HPLC methods better to use than HILIC - FAQ
Read More
Why are ionized polar compounds generally better retained in Aqueous Normal Phase ANP HPLC - FAQ
Read More
Why are the Cogent Silica-C columns more stable than other silica columns - FAQ
Read More
Why do I have lower than normal back pressure with Cogent Diamond Hydride HPLC columns - FAQ
Read More
Why doesn't triphenylamine a tertiary amine retain in Aqueous Normal Phase ANP - FAQ
Read More
Why use buffers during analysis and acid buffers such as the phosphoric acid for column storage solvents for Bidenate C18 columns? Will phosphate precipitate in the column INTERNAL ONLY
Read More
Why would I want to use an HPLC column that is not end capped - FAQ
Read More
Why you should use temperature control with the UDC-Cholesterol column - Tips & Suggestions
Read More
Why your lab should adopt TYPE-C HPLC technology - White Paper
Read More
Will TFA permanently alter retention / selectivity of the Cogent TYPE-C silica columns - FAQ
Read More
Working with ammonium acetate and LCMS requires attention to cleaning - Tips & Suggestions
Read More

© Copyright 2025. MICROSOLV. All Rights Reserved. Website & Hosting by BlueTone Media