Category: ANP Aqueous Normal Phase Articles
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Analyze phosphorylated compounds with the Cogent Diamond Hydride column - Tips & Suggestions
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Analyzing metformin in plasma samples how do I obtain reproducible results and peak shapes - FAQ
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Aqueous Normal Phase ANP and How it is Useful for Polar Compound Separation - Tech Information
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Aqueous Normal Phase ANP Ballistic Gradients Compared to Same in HILIC - Tips & Suggestions
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Aqueous Normal Phase defined & compared to Reversed Phase & Normal Phase definitions HPLC - Tech Information
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Are there HPLC columns that could be used to separate both polar and nonpolar compounds in a single run - FAQ
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Buffer Concentration can Affect ANP Retention of Acids in HPLC Analyses - Tips & Suggestions
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Can I use the Cogent Diamond Hydride column without mobile phase additives like formic acid - FAQ
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Do Tanaka Plots for HPLC apply to columns used with Aqueous Normal Phase ANP methods - FAQ
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Eliminate broad split peaks in Aqueous Normal Phase ANP methods and a methanol diluent- Tips & Suggestions
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Eliminate Retention Time Drift in LCMS With Aqueous Normal Phase ANP Methods - Tips & Suggestions
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How Can I Fix Poor Peak Shape for Phosphorylated Compounds in Aqueous Normal Phase ANP Methods - Tips & Suggestions
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How can I improve accuracy and precision when separating polar compounds by HPLC using Aqueous Normal Phase ANP - FAQ
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How Does Ammonium Fluoride Affect HPLC and LCMS Data if using Aqueous Normal Phase ANP Methods - HPLC Primer
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How to Get Improved Retention and Peak Shape for Glutamine Glutamic Acid and Aspartic Acid - Tips & Suggestions
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Hydrophilic and Hydrophobic Molecules Separation in the Same Aqueous Normal Phase ANP Method - Tips & Suggestions
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I heard that there is not a good alternative to HILIC to achieve sufficient retention for some compounds - FAQ
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Is TFA or formic acid better as an acidic mobile phase additive for Cogent TYPE-C columns - FAQ
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LCMS Challenges with HILIC Mobile Phases from Salt Buildup and Ion Suppression Explained - Tips & Suggestions
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Polar And Non Polar Peptides Analyzed by LCMS with an Aqueous Normal Phase ANP Method - AppNote
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Serum Samples Use Suggestion for Cogent Diamond Hydride Columns in LCMS Methods - Tips & Suggestions
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Should I use methanol as the organic solvent in HPLC when using Aqueous Normal Phase ANP - FAQ
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Simple Sugars Methods using Triethylamine TEA in Aqueous Normal Phase ANP Methods - Tips & Suggestions
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Since Cogent TYPE-C columns can be used in Reversed Phase or Normal Phase what do you suggest to switch these solvent systems which are not miscible - FAQ
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Since Cogent TYPE-C Silica columns use a transition metal catalyst in production what is the presence of any trace quantity on the surface of the stationary phase- FAQ
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Sodium Ion Interference in ANP Methods: Challenges in Analyzing Sodium Succinate - Tips & Suggestions
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Solving Baseline Problems in ANP Methods with the Cogent Diamond Hydride Column - Tips & Suggestions
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Suggestions for HPLC Method Development with TYPE-C Silica Hydride Columns - Tips & Suggestions
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The effect of ionic strength of the mobile phase additive for HPLC columns in Aqueous Normal Phase - Tips & Suggestions
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Type of gradient to use for analysis of hydrophilic and hydrophobic molecules in the same HPLC or LCMS run - Tips & Suggestions
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Using Ammonium Acetate or Ammonium Formate in Diamond Hydride Methods - Tips & Suggestions
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Using methanol instead of acetonitrile in an HPLC method should be done with caution - Tips & Suggestions
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Using two HPLC columns together in a tandem separation for polar and non polar retention - Tips & Suggestions
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What effect does high injection volume have on column performance in Aqueous Normal Phase ANP HPLC- FAQ
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What is the maximum concentration of ammonium fluoride to use in a mobile phase to avoid column damage - Tips & Suggestions
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What is the maximum salt concentration to use with Cogent TYPE-C HPLC columns with HPLC or LCMS - FAQ
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What is the purpose of using isopropanol IPA as part of the mobile phase solvent in ANP methods - FAQ
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What problems can occur when using a dedicated Reversed Phase HPLC instrument for an Aqueous Normal Phase ANP method for the first time - FAQ
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Why am I observing broad split peaks in Aqueous Normal Phase ANP when using acetonitrile and methanol diluents - FAQ
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Why are ionized polar compounds generally better retained in Aqueous Normal Phase ANP HPLC - FAQ
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