Bubbling or fizzing coming from a new Cogent TYPE-C column - Tech Information
July 10, 2013
/
/
/
/
/
/
/
/

The bubbling of gas / liquid that can rarely occur when you remove the end plugs from a brand new Cogent TYPE-C™ column is harmless and does not indicate that the column is damaged.

The escaping gas is a result of the residual solvents and or reagents that were used in the chemical synthesis of the stationary phase and or the column packing process. These solvents or reagents can be trapped in the smaller pores of the silica during the column packing process and escape after time in the column, often after shipping the column.

If you follow the instructions for conditioning the columns, the gas and any residual solvent will be washed away and have no impact on the column life, or your chromatography

Click HERE for more information on Cogent TYPE-C Silica™ HPLC columns

Related Articles

  1. Acetone as the organic mobile phase component - AppNote
  2. Choose an appropriate guard column when using a Cogent TYPE-C HPLC column - How To

© Copyright 2025. MICROSOLV. All Rights Reserved. Website & Hosting by BlueTone Media