Polar and non polar peptides analyzed by LCMS with an Aqueous Normal Phase ANP method - Tips & Suggestions
April 3, 2012
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Suggestion: The Cogent Diamond Hydride™ HPLC columns using Aqueous Normal Phase ANP methods have been shown to be very good choices for LCMS or HPLC analysis of most peptides.
We have published an article on peptides demonstrating the ability of the Diamond Hydride™ stationary phase to retain a very broad range of peptides. This paper uses experimental capillary ID columns due to convenience but the method works just as well with standard LCMS diameter columns.
Click HERE to for an AppNote with method conditions.