Which vial type should I use for a low volume sample study of proteins - FAQ
June 24, 2013
/
/
/
/
/
/
/
/
/
/

 

Choosing the Right Vial for Low-Volume Protein Studies

When working with low-volume protein samples, vial selection plays a critical role in preserving sample integrity and ensuring accurate results. Proteins can adsorb to borosilicate glass surfaces in two primary ways:

  • Through hydroxyl groups or silanols present on untreated glass surfaces
  • Via hydrophobic interactions with the glass itself

These interactions can lead to sample loss, inconsistent concentrations, and compromised data quality.

Recommended Solution: RSA-Pro X™ Vials

Deactivated RSA-Pro X™ vials are specifically designed to address these challenges. They offer:

  • Advanced surface treatment that is more complete than any other glass vial available
  • Non-stick, hydrophobic surface that resists protein binding
  • Hydrolytic stability, even under thermal stress from heating and cooling cycles

This makes RSA-Pro X™ vials the optimal choice for sensitive, low-volume protein applications where sample recovery and consistency are essential.



RSA -Pro X vial product page and demonstration video 



Alternately,
if you can use plastic vials, your best option is most likely using the 300ul LCMS Poly Vials or our 700ul LCMS Poly Vials.


LCMS Poly VialLCMS 300ul Poly Vial
 


 

 

 

Related Articles

  1. Can insert plastic springs be purchased separately - FAQ
  2. How are RSA vials different from all other autosampler vials - FAQ
  3. How do RSA autosampler vials compare against silanized vials for pharma applications - FAQ

© Copyright 2025. MICROSOLV. All Rights Reserved. Website & Hosting by BlueTone Media