Amlodipine, Valsartan, and Hydrochlorothiazide Tablet USP Assay – AppNote

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ARTICLES, APPNOTES, FAQ (9318)
- AppNotes Library (1898)
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  - AppNotes Listed by Column (489)
    
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- Autosampler Vials Information (321)
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- Frequently Asked Questions?? (3409)
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    Knitted Reactor Coils (14)
    
    Tips Liquid Handling (6)
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    Chrom Syringes FAQ (7)
    
    Cogent Column Filters – FAQ (24)
    
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  - HPLC Columns FAQ (819)
    
    2.o™ HPLC Columns FAQ (99)
    
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January 21, 2025
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AppNotes Alternate Generic Methods / AppNotes Library / AppNotes Listed by Column / AppNotes Pharmaceuticals / AppNotes Reversed Phase Methods / AppNotes RP C18 / ARTICLES, APPNOTES, FAQ

Alternate L1 Column used for a USP Assay

This AppNote demonstrates the USP Method for Amlodipine, Valsartan, and Hydrochlorothiazide Tablets working with the Cogent RP C18. As shown in the Chromatograms, the Peak efficiency is superb and USP Peak tailing guidelines are easily met with the Column. This demonstrates a great alternative Column for easy plug and play with this USP Method.

Method Conditions:
Column: Cogent RP C18™ 3um, 100A
Catalog No.: 68318-15P
Dimensions: 4.6 mm x 150 mm
Sample Preparation:
—A: Valsartan/Hydrochlorothiazide standards (0.16/0.025mg per mL)
—B: Valsartan/Amlopidine Sample (3.2/0.1mg per mL)

Note 1: For the full method conditions and details, consult the official United States Pharmacopeia–National Formulary (USP–NF.)

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N0.-381 Amlodipine, Valsartan, and Hydrochlorothiazide pdf 0.1 Mb Download File

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