HPLC Column, RP C18, 3um, 4.6mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
The 68318‑05P Cogent RP C18 HPLC Column is a proven, high‑value reversed‑phase column featuring 3 µm particles and fully double end‑capped C18 bonding, delivering consistent performance, improved efficiency, and reliable retention across a wide range of applications.
Manufactured with high‑purity silica and traditional octadecylsilane (C18) bonding, this stationary phase:
Uses complete end‑capping to reduce silanol activity
Improves peak shape for polar and basic analytes
Provides stable and reproducible chromatography
This column is widely used as a primary analytical column, a USP L1 alternate, and as a scouting column for preparative method development.
50 mm Length – Fast Analysis & Method Screening
Designed for short run times and rapid separations
Lower backpressure compared to longer columns
Ideal for high‑throughput screening (HTS)
Frequently used for method scouting prior to scale‑up
4.6 mm ID – Standard Analytical Performance
Industry‑standard analytical column dimension
Compatible with all conventional HPLC systems
Typical flow rate range: ~0.8–1.5 mL/min
Optimal starting range: ~1.0–1.2 mL/min
Provides:
Strong detector response
Robust method transferability
Reliable performance across laboratories
Why Choose RP C18 (3 µm)
Balanced Efficiency & Pressure
Higher efficiency than 5 µm columns
Lower backpressure than sub‑2 µm UHPLC columns
Ideal balance between performance and system compatibility
Reliable Hydrophobic Retention
Strong reversed‑phase retention for hydrophobic and neutral compounds
Excellent for long‑chain fatty acids and similar analytes
Method Development & Scalability
Ideal for new method development
Frequently used as a scouting column for preparative workflows
Easy scale‑up to longer columns or larger IDs
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Minimizes secondary interactions
Improves peak symmetry
Better performance for basic compounds
High Purity Silica
Consistent column‑to‑column performance
Reduced variability
Reliable results over time
Cost‑Efficient Operation
Lower pressure requirements vs UHPLC columns
Reduced solvent usage with shorter length
Lower overall cost per analysis
Typical Applications
Pharmaceutical and QC analysis
Hydrophobic and neutral compound separations
Long‑chain fatty acids
Method development and optimization
Preparative method scouting
USP L1 applications
Important Usage Notes
Compatible with standard HPLC systems
Monitor pressure when using viscous solvents or longer runs
Ideal for fast method development and screening workflows
Common starting point before method scale‑up