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96‑well plates and sealing mats used in high‑throughput HPLC and LC‑MS workflows for sample containment, evaporation control, and automated handling. This category includes plates and sealing solutions designed for compatibility with autosamplers, robotic systems, and analytical preparation workflows.

These products are typically selected by laboratories performing parallel sample preparation, screening, or batch processing, where consistent geometry, low extractables, and reliable sealing are required.


Plate Quality & Manufacturing Standards

All MICROSOLV™ plastic 96‑well plates in this category are manufactured and tested to ensure suitability for analytical laboratory use, including:

  • Low extractables performance

  • Conformance to ANSI/SLAS (formerly ANSI‑SBS) standards, including footprint

  • Tight dimensional tolerances for automated handling

  • Alphanumeric well grids for sample identification

  • Autoclavable materials

  • Manufactured in an RNase‑ and DNase‑free environment

These characteristics support consistent performance in regulated and research laboratory environments.


Available Plate Configurations

Plates are available in multiple formats to support different sample volumes and workflows, including:

  • Plates with glass inserts

  • Deep‑well plastic plates

  • Medium‑well plastic plates

  • Shallow‑well plastic plates

Well geometry options include:

  • Round or square wells

  • U‑bottom, V‑bottom, or flat‑bottom designs

Selection should be based on sample volume, mixing requirements, and downstream analytical compatibility.


Sealing Mats & Evaporation Control

Sealing mats are used to limit evaporation, contamination, and sample loss during handling or storage. Available sealing options include:

  • Silicone sealing mats

  • Silicone/PTFE composite mats

  • EVA sealing mats

Material selection depends on solvent exposure, temperature conditions, and sealing requirements.


Typical Applications & Use Cases

96‑well plates and sealing mats in this category are commonly used for:

  • High‑throughput HPLC and LC‑MS sample preparation

  • Parallel analytical workflows

  • Screening and method development

  • Laboratory automation and robotic handling

  • Temporary storage and transport of prepared samples


Related Systems

For workflows requiring glass inserts within a 96‑position format, the U‑2D™ Micro‑Sample Management System can be used as an alternative approach that combines autosampler‑grade glass inserts with a plate‑style handling format.

👉 View the U‑2D™ Micro‑Sample Management System

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