HPLC Column, NP Diol, 10um, 4.0mm ID x 250mm Length, 100A. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Cogent NP Diol™ HPLC Columns are designed for Normal Phase and HILIC separations of hydrophilic and polar compounds. Manufactured using ultra-high purity silica bonded with a short hydrocarbon ligand containing a terminal diol functional group, this stationary phase provides consistent retention and selectivity while offering improved robustness compared to unmodified silica. NP Diol™ is an excellent alternative for USP L20 methods and is widely used for both established methods and new method development.
82060-25P-4 is packed with 10 µm NP Diol™ particles in a 4.0 mm ID x 250 mm format with a 100Å pore size. The larger 10 µm particle size allows operation at higher flow rates while generating lower backpressure than smaller particle columns. The extended 250 mm column length provides maximum resolving power and increased peak capacity, making it ideal for complex separations, method optimization, and analytical applications requiring the highest level of chromatographic resolution.
The NP Diol™ stationary phase is non-end-capped and is frequently chosen as a replacement for unmodified silica columns due to its enhanced durability and broader solvent compatibility. While selectivity may differ slightly from bare silica, it provides excellent performance for hydrophilic and polar compounds in both HILIC and Normal Phase chromatography. This stationary phase is often selected when maximum retention, resolution, and reproducibility are required.
Key Benefits
NP Diol™ stationary phase
USP L20 equivalent chemistry
Ultra-high purity silica support
Terminal diol functional group
Non-end-capped chemistry
100Å pore size
10 µm particle size
Suitable for Normal Phase chromatography
Suitable for HILIC applications
Maximum resolution for demanding separations
Typical Applications
Normal Phase HPLC
HILIC chromatography
USP L20 methods
Polar compound separations
Hydrophilic compound analysis
Carbohydrate analysis
Pharmaceutical analysis
Food and beverage testing
Method development
Quality control testing
Specifications
Product Type: HPLC Column
Stationary Phase: NP Diol™
Chromatography Mode: Normal Phase / HILIC
USP Classification: L20
Particle Size: 10 µm
Pore Size: 100Å
Column Dimensions: 4.0 mm ID x 250 mm
Recommended Flow Rate: 0.8–1.5 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Special Order Item Information
Please review the Special Order Item Information for complete details.
For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.
Important Notes
Suitable for Normal Phase chromatography
Suitable for HILIC applications
USP L20 equivalent chemistry
Non-end-capped stationary phase
Alternative to unmodified silica columns
Improved robustness compared to bare silica phases
Compatible with a wide range of solvents
10 µm particles allow higher flow rates with lower backpressure
250 mm length provides maximum retention, resolution, and peak capacity
Designed for hydrophilic and polar compound analysis
This is a Special Order Item