Semi Prep Guard Column Cartridge, NP Silica Wide Pore, 5um, 300A. 10mm ID x 10mm Length. Cogent Brand. 5/PK.

Additional Information:

Cogent NP Silica™ Wide Pore Semi-Preparative Guard Column Cartridges are designed to protect semi-preparative HPLC columns from particulate contamination and strongly retained compounds that can reduce column performance and shorten column life. Packed with the same high-purity stationary phase as the analytical column, these guard cartridges help maintain chromatographic performance while reducing replacement costs for valuable semi-preparative columns.

82561-SP-PG1-3 Guard Column Cartridges are packed with 5 µm NP Silica™ Wide Pore stationary phase manufactured from ultra-high purity, low-metal-content 300 Å silica. This unmodified silica stationary phase provides traditional USP L3 selectivity while the wide pore structure improves accessibility for proteins, peptides, and other larger biomolecules. Packed in stainless steel cartridges with stainless steel frits, they are designed to intercept contaminants before they reach the primary separation column.

The 10 mm ID x 10 mm format is specifically designed for use with compatible 10 mm ID semi-preparative column systems operating in HILIC and normal-phase modes. Routine guard cartridge replacement helps maintain column efficiency, reduce downtime, and extend semi-preparative column service life.

Key Benefits

  • NP Silica™ Wide Pore stationary phase

  • USP L3 equivalent chemistry

  • Ultra-high purity, low-metal-content silica

  • Unmodified silica surface

  • 300 Å wide pore structure

  • Suitable for HILIC applications

  • Suitable for normal-phase chromatography

  • Protects semi-preparative columns from contamination

  • Extends column lifetime

  • Stainless steel cartridge construction with stainless steel frits

Typical Applications

  • Semi-preparative HILIC chromatography

  • Semi-preparative normal-phase HPLC

  • Protein purification

  • Peptide purification

  • Biomolecule purification

  • Lipid purification

  • Process development

  • Fraction collection

  • Semi-preparative column protection

  • Routine guard cartridge replacement

Specifications

  • Product Type: Semi-Preparative Guard Column Cartridge

  • Stationary Phase: NP Silica™ Wide Pore

  • Chromatography Mode: HILIC / Normal Phase

  • USP Classification: L3

  • Particle Size: 5 µm

  • Pore Size: 300 Å

  • Cartridge Dimensions: 10 mm ID x 10 mm

  • Construction: Stainless Steel Cartridge

  • Frit Material: Stainless Steel

  • Quantity: 5 Pack

  • Brand: Cogent

Guard Column Requirements

Special Order Item Information

Important Notes

  • Suitable for HILIC applications

  • Suitable for normal-phase chromatography

  • Unmodified silica stationary phase

  • USP L3 equivalent chemistry

  • Wide pore design improves accessibility for proteins, peptides, and larger molecules

  • Protects semi-preparative columns from particulates and strongly retained contaminants

  • Helps extend column lifetime and maintain performance

  • Designed specifically for 10 mm ID semi-preparative columns

  • Requires a compatible Cogent Guard Column Holder

  • Intended for routine replacement as part of preventive maintenance

  • Package contains five guard column cartridges

  • This is a Special Order Item


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