Prep Guard Column Cartridge, NP Silica, Wide Pore, 5um, 300A. 21.2mm ID x 10mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent NP Silica™ Wide Pore Preparative Guard Column Cartridges are designed to protect preparative HPLC columns from particulate contamination and strongly retained compounds that can reduce column performance and shorten column life. Packed with the same high-purity stationary phase as the analytical column, these guard cartridges help maintain chromatographic performance while reducing replacement costs for valuable preparative columns.
82561-P21-PG1-3 is packed with 5 µm NP Silica™ Wide Pore stationary phase manufactured from ultra-high purity, low-metal-content 300 Å silica. This unmodified silica stationary phase provides traditional USP L3 selectivity while the wide pore structure improves accessibility for larger molecules such as proteins, peptides, and other biomolecules. Mounted in a stainless steel cartridge with stainless steel frits, it is designed to trap contaminants before they reach the preparative column.
The 21.2 mm ID x 10 mm format is specifically designed for use with compatible 21.2 mm ID preparative column systems operating in HILIC and normal-phase modes. Routine guard cartridge replacement helps maintain preparative column efficiency, reduce downtime, and extend column service life.
Key Benefits
NP Silica™ Wide Pore stationary phase
USP L3 equivalent chemistry
Ultra-high purity, low-metal-content silica
Unmodified silica surface
300 Å wide pore structure
Protects preparative columns from contamination
Extends preparative column lifetime
Stainless steel cartridge construction
Stainless steel frits
Ideal for HILIC and normal-phase chromatography
Typical Applications
Preparative HILIC chromatography
Preparative normal-phase HPLC
Protein purification
Peptide purification
Biomolecule purification
Polar compound purification
Method scale-up
Process development
Preparative column protection
Routine guard cartridge replacement
Specifications
Product Type: Preparative Guard Column Cartridge
Stationary Phase: NP Silica™ Wide Pore
Chromatography Mode: HILIC / Normal Phase
USP Classification: L3
Particle Size: 5 µm
Pore Size: 300 Å
Cartridge Dimensions: 21.2 mm ID x 10 mm
Construction: Stainless Steel Cartridge
Frit Material: Stainless Steel
Brand: Cogent
Guard Column Requirements
Requires a Cogent 21.2 mm ID Preparative Guard Column Holder (Catalog No. 83000-P21-GH).
Designed for use with compatible Cogent NP Silica™ Wide Pore 21.2 mm ID preparative HPLC columns.
Special Order Item Information
Please review the Special Order Item Information for complete details.
For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.
Important Notes
Suitable for HILIC applications
Suitable for normal-phase chromatography
Unmodified silica stationary phase
USP L3 equivalent chemistry
Wide pore design improves accessibility for proteins, peptides, and larger molecules
Protects preparative columns from particulates and strongly retained contaminants
Helps extend column lifetime and maintain performance
Designed specifically for 21.2 mm ID preparative column systems
Requires a compatible Cogent Guard Column Holder
Intended for routine replacement as part of preventive maintenance
This is a Special Order Item