Prep HPLC Column, NP Silica, 10um, 100A. 30mm ID x 250mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent NP Silica™ Preparative HPLC Columns are trusted by leading laboratories worldwide for compound purification, method scale-up, and process chromatography applications. Manufactured from ultra-high purity, low metal content, 100Å silica that remains completely unmodified, this stationary phase provides the native silica selectivity required for the purification of lipids, hydrophilic compounds, polar analytes, and other challenging sample types. Suitable for both HILIC and Normal Phase chromatography, this stationary phase is equivalent to USP L3 silica chemistry and has been successfully used for many years in pharmaceutical, cannabis, chemical, and forensic laboratories around the world.
82061-P30-250 is packed with 10 µm NP Silica™ particles in a 30 mm ID x 250 mm preparative column format. The larger particle size enables operation at higher flow rates while producing substantially lower backpressure than smaller particle columns. The 30 mm internal diameter provides very high sample loading capacity, while the 250 mm column length maximizes retention, peak capacity, and chromatographic resolution for demanding preparative and purification workflows.
The 10 µm particle design has made this column a proven choice for preparative HPLC, purification method development, and process-scale separations worldwide. Because the stationary phase chemistry remains consistent across analytical, preparative, and purification formats, methods developed on analytical NP Silica™ columns can often be scaled directly to larger ID columns with predictable chromatographic behavior. This makes the column especially valuable for production purification, compound isolation, impurity collection, process development, and large-scale purification operations requiring world-class performance and reliable scale-up.
Key Benefits
NP Silica™ stationary phase
USP L3 equivalent chemistry
Ultra-high purity silica
Low metal content silica
Unmodified silica surface
100Å pore size
10 µm particle size
Lower operating backpressure
Very high sample loading capacity
Proven for preparative HPLC and purification
Typical Applications
Preparative HPLC
Compound purification
Lipid purification
Polar compound separations
Hydrophilic compound purification
HILIC chromatography
Normal Phase chromatography
Pharmaceutical purification
Cannabis purification
Forensic laboratory applications
Specifications
Product Type: Preparative HPLC Column
Stationary Phase: NP Silica™
USP Classification: L3
Chromatography Modes: HILIC and Normal Phase
Particle Size: 10 µm
Pore Size: 100Å
Column Dimensions: 30 mm ID x 250 mm
Recommended Flow Rate: 30–80 mL/min
Sample Loading Capacity: Preparative Scale
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for HILIC and Normal Phase chromatography
USP L3 equivalent stationary phase
Unmodified silica surface chemistry
Manufactured from ultra-high purity, low metal content silica
Designed for purification of hydrophilic, polar, and charged compounds
Lower operating pressure than smaller particle preparative columns
Very high loading capacity for compound isolation and purification
Frequently used in pharmaceutical, cannabis, chemical, and forensic laboratories worldwide
Proven preparative HPLC technology used globally for many years
Directly scalable from analytical NP Silica™ column methods
Excellent for purification method development, process scale-up, and production chromatography
Requires a preparative HPLC system capable of supporting flow rates of approximately 30–80 mL/min and larger column dimensions
250 mm length provides maximum retention, peak capacity, and chromatographic resolution for demanding purification applications
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