Semi Prep HPLC Column, NP Diol, 10um, 100A. 10mm ID x 250mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent NP Diol™ Semi-Prep HPLC Columns are designed for purification of polar and hydrophilic compounds using Normal Phase and HILIC chromatographic modes. Manufactured using ultra-high purity silica bonded with a short hydrocarbon ligand containing a terminal diol functional group, this stationary phase provides reproducible retention characteristics and selectivity for compounds that may be difficult to retain or purify using traditional reversed-phase methods. NP Diol™ is often selected as an alternative to unmodified silica columns when improved stability and polar selectivity are desired.
82060-SP250 is packed with 10 µm NP Diol™ particles in a 10 mm ID x 250 mm semi-preparative format with a 100Å pore size. The 10 µm particle size is well suited for semi-preparative chromatography, providing lower operating backpressure while allowing higher flow rates and increased sample loading compared to analytical columns. The 250 mm column length provides maximum resolving power and increased peak capacity, making it ideal for demanding purification applications and complex sample separations.
The NP Diol™ stationary phase is non-end-capped and is ideal for purification of hydrophilic and polar compounds using either Normal Phase or HILIC conditions. The semi-preparative column format provides an excellent balance between purification capacity and chromatographic efficiency, making it suitable for method scale-up, compound isolation, and fraction collection applications. NP Diol™ columns are frequently selected when maximum resolution is required for preparative separations.
Key Benefits
NP Diol™ stationary phase
Ultra-high purity silica support
Terminal diol functional group
Non-end-capped chemistry
100Å pore size
10 µm semi-preparative particle size
Suitable for Normal Phase chromatography
Suitable for HILIC applications
Increased loading capacity versus analytical columns
Maximum resolution for compound purification
Typical Applications
Semi-preparative HPLC
Compound purification
HILIC purification
Normal Phase purification
Polar compound isolation
Hydrophilic compound purification
Natural product purification
Pharmaceutical research
Method scale-up
Fraction collection applications
Specifications
Product Type: Semi-Prep HPLC Column
Stationary Phase: NP Diol™
Chromatography Mode: Normal Phase / HILIC
Particle Size: 10 µm
Pore Size: 100Å
Column Dimensions: 10 mm ID x 250 mm
Recommended Flow Rate: 3–8 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Special Order Item Information
Please review the Special Order Item Information for complete details.
For pricing confirmation, availability, lead times, or application assistance, please contact MICROSOLV Customer Service.
Important Notes
Suitable for Normal Phase chromatography
Suitable for HILIC applications
Designed for purification of hydrophilic and polar compounds
Alternative to unmodified silica columns
Higher loading capacity than analytical columns
10 µm particles provide lower backpressure at semi-preparative flow rates
10 mm ID format requires a semi-preparative capable HPLC system
250 mm length provides maximum retention, resolution, and peak capacity
Intended for compound isolation and purification workflows
This is a Special Order Item