Semi Prep HPLC Column, NP Diol, 10um, 100A. 10mm ID x 150mm Length. Cogent Brand. 1 EA.

Additional Information:

Cogent NP Diol™ Semi-Prep HPLC Columns are designed for purification of polar and hydrophilic compounds using Normal Phase and HILIC chromatographic modes. Manufactured using ultra-high purity silica bonded with a short hydrocarbon ligand containing a terminal diol functional group, this stationary phase provides reproducible retention characteristics and selectivity for compounds that may be difficult to retain or purify using traditional reversed-phase methods. NP Diol™ is often selected as an alternative to unmodified silica columns when improved stability and polar selectivity are desired.

82060-SP150 is packed with 10 µm NP Diol™ particles in a 10 mm ID x 150 mm semi-preparative format with a 100Å pore size. The 10 µm particle size is well suited for semi-preparative chromatography, providing lower operating backpressure while allowing higher flow rates and increased sample loading compared to analytical columns. The 150 mm column length provides enhanced resolving power and purification efficiency while maintaining practical solvent consumption for laboratory-scale purification.

The NP Diol™ stationary phase is non-end-capped and is ideal for purification of hydrophilic and polar compounds using either Normal Phase or HILIC conditions. The semi-preparative column format provides an excellent balance between purification capacity and chromatographic resolution, making it suitable for method scale-up, compound isolation, and fraction collection applications. NP Diol™ columns are frequently selected for purification workflows requiring an alternative to unmodified silica stationary phases.

Key Benefits

  • NP Diol™ stationary phase

  • Ultra-high purity silica support

  • Terminal diol functional group

  • Non-end-capped chemistry

  • 100Å pore size

  • 10 µm semi-preparative particle size

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • Increased loading capacity versus analytical columns

  • Enhanced resolution for compound purification

Typical Applications

  • Semi-preparative HPLC

  • Compound purification

  • HILIC purification

  • Normal Phase purification

  • Polar compound isolation

  • Hydrophilic compound purification

  • Natural product purification

  • Pharmaceutical research

  • Method scale-up

  • Fraction collection applications

Specifications

  • Product Type: Semi-Prep HPLC Column

  • Stationary Phase: NP Diol™

  • Chromatography Mode: Normal Phase / HILIC

  • Particle Size: 10 µm

  • Pore Size: 100Å

  • Column Dimensions: 10 mm ID x 150 mm

  • Recommended Flow Rate: 3–8 mL/min

  • Column Hardware: Stainless Steel

  • Brand: Cogent

Special Order Item Information

Important Notes

  • Suitable for Normal Phase chromatography

  • Suitable for HILIC applications

  • Designed for purification of hydrophilic and polar compounds

  • Alternative to unmodified silica columns

  • Higher loading capacity than analytical columns

  • 10 µm particles provide lower backpressure at semi-preparative flow rates

  • 10 mm ID format requires a semi-preparative capable HPLC system

  • 150 mm length provides enhanced resolution and purification efficiency

  • Intended for compound isolation and purification workflows

  • This is a Special Order Item


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